Biosynthesis of Selenium Nanoparticles and their Biological and Pharmaceutical Applications

- Authors: Satabdi Mishra1, Banishree Sahoo2, Manoranjan Arakha3
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View Affiliations Hide Affiliations1 Center for Biotechnology, Siksha O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751030, India 2 Center for Biotechnology, Siksha O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751030, India 3 Center for Biotechnology, Siksha O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751030, India
- Source: Nanomaterials in Biological Milieu: Biomedical Applications and Environmental Sustainability , pp 42-56
- Publication Date: June 2025
- Language: English


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Numerous methods have been established to fabricate nanoparticles with varying physico-chemical properties to suit the applications. However, because of ecofriendly, non-toxic, and cost-effective approaches, fabrication methods have attracted the interest of many research groups to synthesize different nanoparticles, especially for biological and pharmaceutical applications. In this context, microorganisms and plant extracts are widely utilized for the bio-fabrication of nanoparticles. Hence, this chapter intends to discuss the bio-fabrication of selenium nanoparticles and their biological applications. In this context, SeNPs have antioxidative, antimicrobial, and anticancer activities. Hence, SeNP has a broad range of therapeutic effects and is often used to treat various diseases, including diabetes, cancer, arthritis, etc. Selenium nanoparticles can be used for numerous pharmaceutical applications, such as gene and drug delivery. Additionally, SeNPs are used for environmental remediation and nanobiosensors, which can be used to detect pathogens, nucleic acids, antibodies, etc. To this end, the chapter will explore the potential of biological agents for the biofabrication of nanoparticles and their application in different pharmaceutical industries.
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