Semisynthetic Resveratrol-derived Systems: A Synergism between Nature and Organic Synthesis
- Authors: Antonella Capperucci1, Damiano Tanini2
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View Affiliations Hide Affiliations1 Department of Chemistry Ugo Schiff, University of Florence, Via della Lastruccia 13, I 50019 Sesto Fiorentino, Italy 2 Department of Chemistry Ugo Schiff, University of Florence, Via della Lastruccia 13, I-50019 Sesto Fiorentino, Italy
- Source: Flavonoids and Phenolics , pp 249-271
- Publication Date: November 2022
- Language: English
Semisynthetic Resveratrol-derived Systems: A Synergism between Nature and Organic Synthesis, Page 1 of 1
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Structural modifications of the resveratrol scaffold are valuable tools in order to develop new derivatives with potential biomedical and pharmacological applications. The investigation of the biological properties of resveratrol-derived semisynthetic systems and the study of their structure-activity relationships are attracting growing interest from medicinal chemists and biologists. In this context, the synthesis of novel resveratrol-derived systems characterisaed by elevated molecular complexity is highly sought after. Over the past years, a wide variety of resveratrol derivatives have been prepared and studied for their biological properties. Therefore, a number of stilbenoid-related potential anticancer, antioxidant, antiviral, analgesic, and anti-neurodegenerative systems have been investigated. This chapter focuses on recent studies related to the preparation and the study of semisynthetic resveratrol-derived systems.
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