Beta Glucan For The Treatment Of Recurrent Aphthous Stomatitis And Diabetic Ulcers

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<div&gt;Recurrent Aphthous Stomatitis (RAS), which has symptoms like pain while&lt;/div&gt;<div&gt;eating, speaking, or swallowing, is one of the most hurtful oral mucosal inflammatory&lt;/div&gt;<div&gt;ulcerative diseases [1]. Tumor necrosis factor α (TNF α), has a main role in&lt;/div&gt;<div&gt;predominantly cell-mediated immune response due to the pathogenesis of RAS. The&lt;/div&gt;<div&gt;aim of this study was to investigate the therapeutic effects of Beta-glucan on the&lt;/div&gt;<div&gt;response of lymphocytes with and without phytohemagglutinin (PHA), a T lymphocyte&lt;/div&gt;<div&gt;mitogen, in treatment of RAS. RAS, estimated by the Ulcer Severity Score (USS),</div&gt;<div&gt;shows ulcer characteristics (number, size, duration, ulcer-free period, site, and pain).</div&gt;