Beta Glucan Against Coronavirus

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new virus that is the source of COVID-19 pandemic and causing great damage all over the world. Among the main accelerating factors of mortality due to COVID-19 are the direct endothelial damage caused by coronaviruses and the defect in the clotting mechanism due to the cytokine storm. These two main destructive factors are deeply related the dysregulation of the immune system. The comorbidities and ethnic variations are also effecting the risk of associated thrombogenic disruption. Beta glucans are gathering a wide range of attention due to their immunostimulating effect, drug potential, and biologically active nature against many diseases by boosting the immune system. In this review, the healing and positive effect of the biological response modifier, beta glucan, on COVID-19’s symptoms such as cytokine storm, coagulopathy, lung inflammation causing mortality by modulating the immune system are discussed.