Beta Glucan for the Treatment of Human Papilloma Virus (HPV) and Cervical Cancer
- By Betül Gürünlü1
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View Affiliations Hide AffiliationsAffiliations: 1 "Üsküdar Üniversitesi,Biyomühendislik Bölümü,Merkez Yerleşke A Blok 325/AAltunizade, Üsküdar, İstanbul, Turkey"
- Source: Medical Applications of Beta-Glucan , pp 130-142
- Publication Date: January 2022
- Language: English
Cervical cancer is the fourth most frequently diagnosed cancer. For the treatment of this relentless disease, chemotherapy is the most widely applied cure now. However, this treatment carries some important side effects, such as neutropenia which having an abnormally low concentration of neutrophils in the blood. Also, chemotherapeutic drugs cause harm to blood formation. Therefore, chemotherapy affects the patients’ immune system badly by making them open to infections. Another treatment method is radiotherapy for the healing of cervical cancer. This technique also carries some side effects being hematopoietic and harm to the immune system. Betaglucans modulates the immune system by affecting a wide range of cells like antigenpresenting cells (APCs), including macrophages, dendritic cells, T cells, monocytes. It regulates both adaptive and innate immune systems. It has different kinds such as sizofiran (SPG), zymosan, curdlan, and PBG to prevent and protect from cervical cancer. Beta-glucan provides a novel therapeutic method for the healing of human papillomavirus (HPV) and cervical cancer.
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