Remarkable Advances in the Asymmetric Synthesis of Biologically Active Natural Compounds from the Advent of Chiral Auxiliaries
- Authors: Gaspar Diaz Muñoz1, Izabel Luzia Miranda2, Suélen Karine Sartori3, Daniele Cristina de Rezende4, Jefferson Viktor Barros de Paula Baeta5, Fernanda Rodrigues Nascimento6, Marisa Alves Nogueira Diaz7
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View Affiliations Hide Affiliations1 Department of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil 2 Department of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil 3 Department of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil 4 Department of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil 5 Department of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil 6 Department of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil 7 Department of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil
- Source: Advances in Organic Synthesis: Volume 13 , pp 1-51
- Publication Date: November 2020
- Language: English
Remarkable Advances in the Asymmetric Synthesis of Biologically Active Natural Compounds from the Advent of Chiral Auxiliaries, Page 1 of 1
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This chapter reports advances in synthetic methodologies employing chiral auxiliaries for the stereoselective synthesis of biologically active natural molecules. Derivatives of naturally occurring compounds such as amino acids, carbohydrates, and terpenes, chiral auxiliaries have been described as an essential aid for the construction of highly complex molecules. Among these auxiliaries, we highlight those of Evans, Corey, Yamada, Enders, Oppolzer, Kunz, Meyers, and Schöllkopf, whose contributions led to a remarkable progress in asymmetric synthesis in the last decades and continue to bring advances until the present day.
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