Aluminium and other Metals Exposure Cause Neurological Disorders: Evidence from Clinical/ human Studies
- Authors: Zehra Batool1, Laraib Liaquat2, Tuba Sharf Batool3, Rida Nisar4, Saida Haider5
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View Affiliations Hide Affiliations1 Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan 2 Multidisciplinary Research Lab, Bahria University Medical and Dental College, Bahria University, Karachi, Pakistan 3 Atta ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Pakistan 4 HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan 5 Neurochemistry and Biochemical Neuropharmacology Research Unit, Department of Biochemistry, University of Karachi, Karachi, Pakistan
- Source: Biochemical Mechanisms of Aluminium Induced Neurological Disorders , pp 97-146
- Publication Date: December 2021
- Language: English
Aluminium and other Metals Exposure Cause Neurological Disorders: Evidence from Clinical/ human Studies, Page 1 of 1
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Exposure to Aluminium and other heavy metals has become a serious concern in todays modern life. Due to excessive use and improper disposal of heavy metals, the entire food chain is being contaminated, which is imposing various health risks for humans and other living organisms. These heavy metals particularly induce oxidative stress through different mechanisms which can ultimately interfere with the normal physiological activities. Brain is highly prone to oxidative stress due to its rich polyunsaturated content and high oxygen consumption than the periphery. Therefore, emphasis has been given to neurotoxicological effects produced by exposure to heavy metals. In this regard, the effects of both essential and non-essential heavy metals have been investigated in various clinical studies which are demonstrating them as a serious threat to normal brain function. This chapter summarizes the neurotoxicological effects of heavy metals which have been revealed in various human studies.
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