Mammalian Sperm Guidance — An Overview

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In the recent two decades mammalian spermatozoa were demonstrated to perform chemotaxis, thermotaxis and rheotaxis. It is believed that in the Fallopian tube spermatozoa are first guided to the fertilization site by long-range mechanisms, thermotaxis and rheotaxis, and there they are guided to the egg by two processes of chemotaxis, considered a short-range mechanism. The occurrence of chemotaxis and thermotaxis in additional locations along the female genital tract cannot be excluded.