Polymeric Nanocapsules
- Authors: Mihaela Holban1, Delia Iurea (Raţă)2, Marcel Popa3
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View Affiliations Hide Affiliations1 “Al.I.Cuza” University, Faculty of Chemistry, Department of Organic Chemistry, Carol I Blv., no.11, 700506, Iasi Romania 2 “Gheorghe Asachi” Technical University of Iasi, Faculty of Chemical Engineering and Environmental Protection, Department of Natural and Synthetic Polymers, Prof. dr. docent Dimitrie Mangeron Str., no. 73, 700050, Iasi, Romania 3 “Gheorghe Asachi” Technical University of Iasi, Faculty of Chemical Engineering and Environmental Protection, Department of Natural and Synthetic Polymers, Prof. dr. docent Dimitrie Mangeron Str., no. 73, 700050, Iasi, Romania
- Source: Polymeric Nanomedicines , pp 412-449
- Publication Date: May 2013
- Language: English
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Polymer nanocapsules are widely used in the biomedical field, especially as carriers for controlled drug delivery. The main preparation methods are described in the paper (nanoprecipitation, emulsion-diffusion, double emulsification, emulsion-coacervation, polymer-coating, layer-by-layer and interfacial polycondensation), emphasizing the role of different parameters on drug encapsulation efficiency and drug release profiles. Mechanisms of drug loading and releasing are also shortly discussed. The paper ends with the presentation of the major biomedical applications (drug delivery and diagnosis) of polymer nanocapsules, the discussion being directed toward several routes of drug administration.
Hardbound ISBN:
9781608056286
Ebook ISBN:
9781608054848
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