Enantioselective Electrophilic Fluorination: The Complete Story
- Authors: C. Audouard, J. A. Ma, D. Cahard3
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View Affiliations Hide Affiliations3 UMR 6014 CNRS, Institut de Recherche en Chimie Organique Fine (IRCOF) Universite de Rouen, F-76821 Mont Saint Aignan Cedex, France.
- Source: Advances in Organic Synthesis: Volume 2 , pp 431-461
- Publication Date: January 2006
- Language: English
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Progress in the field of enantioselective electrophilic fluorination during the past eighteen years resulting from fascinating research conducted by twelve international groups is reviewed. Two complementary strategies for the synthesis of enantiopure fluorine-containing molecules currently define state-of-the-art in this area. The use of chiral, non-racemic fluorinating agents is the most general approach while catalytic methods using either transition-metal catalysts or organocatalysts apply to specific substrates.
Hardbound ISBN:
9781608056446
Ebook ISBN:
9781608051984
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