Bentham Science Publishers

Ypt/Rab GTPases form the largest branch of the Ras-related small GTPase superfamily and regulate intracellular membrane trafficking in all eukaryotes. Since their discovery over two decades ago, a wealth of information has accumulated about the roles that Ypt/Rab proteins play in vesicular transport steps, including vesicle budding, movement, and fusion. In recent years, Ypt/Rab GTPases and membrane trafficking have been discovered to play an important role in other cellular processes, such as signal transduction, cell growth and differentiation. Additionally, Rab GTPases have been implicated in various human diseases, ranging from diabetes to cancer. This e-book provides a timely update on the rapidly developing field and discusses all functional aspects of Ypt/Rab GTPases. The 12 chapters cover well-characterized Ypts/Rabs involved in both exocytic and endocytic pathways as well as newly identified and uncharacterized Rab GTPases. A comprehensive picture about how each Ypt/Rab controls multiple vesicular trafficking steps via interactions with multiple effectors is conveyed to the reader’s mind.

This e-book is the first ever volume focused on the Ypt/Rab GTPases and should provide a useful resource for researchers, students and teachers interested in the field.

Radiation Processes In Crystal Solid Solutions is a monograph explaining processes occurring in two classes of crystal solids (metal alloys and doped alkali halides) under irradiation by various types of radiation (alpha, beta, gamma, X-radiations, ions). While metal alloys may differ in high radiation stability, solid solutions based on alkali halides are very radiation-sensitive materials. Radiation defect production mechanisms, intrinsic and extrinsic radiation defects, a role of complexes an impurity-radiation defect which explain distinction in radiating stability of the specified classes of solid solutions are discussed in this e-book. To describe radiation induced phase transformations, two approaches are highlighted: kinetic and thermodynamic. This e-book also includes research on the effect of small radiation doses in a structurally solid phase state of a solution along with a semi-quantitative estimation of radiation effects with respect to temperature changes. This e-book should be a useful reference for advanced readers interested in the physics of radiation and solid state physics.

Rare-earth hexaborides are a group of materials composed of octahedral boron units. They are useful for making advanced ceramics that have a wide range of industrial applications due to their low electronic work functions, hardness, refractory properties, low electrical resistances and specific thermal expansion coefficients.

Rare-Earth Metal Hexaborides: Synthesis, Properties, and Applications provides a quick reference on rare-earth metal hexaborides and their engineering applications. It provides a primer on rare earth elements followed by details of rare-earth hexaboride structures, synthetic methods, and information about their alloys and ceramic composites. References to scholarly research are also provided for assisting advanced readers.

This reference is a handy source of information for chemical engineering and materials science scholars, and anyone interested in the applied chemistry of rare-earth metals and borides.

Recent Advancements in Multidimensional Applications of Nanotechnology provides a comprehensive overview of the latest advancements and applications of nanotechnology across various dimensions. Covering a wide range of topics, from electron microscopy to nanotherapeutic strategies, the book explores the diverse applications of nanotechnology in industries and research fields.

Key Features:

Comprehensive Coverage: Gain insights into electron microscopy, biogenic synthesis methods, energy applications, and more.

Industry Applications: Discover how nanotechnology is revolutionizing industries such as energy, oil and gas, agriculture, and healthcare.

Cutting-Edge Developments: Stay ahead of the curve with discussions on copper oxide nanoparticles, nano-coatings, and thin film optimization for solar cells.

Biomedical Breakthroughs: Explore the exciting realm of biomedical applications, from metallic nanoparticles in healthcare to biogenic synthesis methods.

Practical Insights: Benefit from practical insights and case studies that showcase real-world applications of nanotechnology.

Type A acute aortic dissection (TAAAD) is an acute cardiovascular condition that is normally associated with genetic conditions such as Marfan Syndrome, but it can also occur in patients with no known predisposing risk factors. TAAD is associated with extremely high mortality (over 20% of documented cases in medical literature) if not addressed on time. Surgical management of TAAAD also varies tremendously depending on the causative pathology. Techniques to manage TAAAD cover the entire spectrum of methods employed in cardiac surgery ranging from a simple replacement of the ascending aorta to aortic root sparing or replacement, and an aortocoronary bypass to total arch and descending aortic stenting involving hypothermic circulatory arrest or other cerebral protection strategies. New medical evidence suggests that concomitant, intraoperative management of the arch and descending aorta minimizes the need for subsequent surgeries in patients who are operated upon for TAAAD. Coupled with new diagnostic technology available to medical professionals, better long-term patient outcomes for TAAD treatment are now a reality.

Recent Advances in Acute Type A Aortic Dissection presents a collection of comprehensive reviews from many experts on TAAAD. Cardiac surgeons can benefit from this volume by learning about current medical opinions and consensuses on risk factors (including genetic predisposition), diagnostic modalities, intraoperative management, surgical options, cerebral protection strategies, and long-term follow up procedures on acute TAAAD.

Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents a selection of chapters that explain different analytical techniques and their use in applied research. Readers will find updated information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis.

The third volume of the series features seven reviews on a variety of techniques:

· Chiral Analysis of Methamphetamine and Related Controlled Substances in Forensic Science

· Low-cost feedstocks for biofuels and high value added products production: Using multi-parameter flow cytometry as a tool to enhance the process efficiency

· Recent Trends in the Application of Ionic Liquids for Micro Extraction Techniques

· Electrospun Nanofibers: Functional and Attractive Materials for the Sensing and Separation Approaches in Analytical Chemistry

· Neutron Activation Analysis: An Overview

· Non-commercial Polysaccharides-based Chiral Selectors in Enantioselective Chromatography

· Ru(II)-polypyridyl Complexes as Potential Sensing Agents for Cations and Anions.

Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents a selection of chapters that explain different analytical techniques and their use in applied research. Readers will find updated information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis.

The fifth volume of the series features five reviews which demonstrate chemical analysis techniques applied in different disciplines.

- Superior Aspects of Liquid Chromatography-Based Mass Spectrometers in Chiral Analysis

- New Trends in Sample Preparation for Pharmaceutical and Biological Analysis by Chromatographic Methods

- Qualitative and Quantitative Investigation of Bio Tissues using Microscopy and Data Mining

- Analytical Techniques For Analysis of Metals and Minerals in The Soil Samples

- Monitoring Therapeutic Response in Cancers: A Raman Spectroscopy Approach

The book presents recent advances in the field of angiogenesis and antiangiogenesis. Starting with the hypothesis of Judah Folkman that tumor growth is angiogenesis dependent, this area of research now has a solid scientific foundation. Tumor growth, metastasis, progression, dormancy and apoptosis depend on angiogenesis: several clinical studies have shown a positive correlation between the number of vessels in the tumor, metastasis formation and disease prognosis. A number of approaches have been developed to inhibit tumor angiogenesis, and numerous compounds discovered that inhibit angiogenesis, but only a few of them proved effective in vivo and only a couple of agents were able to induce tumor regression. These and other related developments described in the book should prove to be of interest to a large number of readers wishing to keep abreast with the latest developments in the field.

Biomedical signal processing is a rapidly expanding field with a wide range of applications, from the construction of artificial limbs and aids for disabilities to the development of sophisticated medical imaging systems. Acquisition and processing of biomedical signals has become more important to the physician. The main reasons for this development are the growing complexity of the biomedical examinations, the increasing necessity of comprehensive documentation and the need for automation in order to reduce costs. Analysis of signals accomplished by humans has many limitations, therefore, computer analysis of these signals could provide objective strength to diagnoses; however, the development of an algorithm for biomedical signal analysis is a significant challenge. This ebook will cover biomedical signal processing as used in both therapeutic and diagnostic instrumentation. A number of current research projects are also outlined with emphasis on intelligent medical image diagnosis. This book should be a valuable reference for researchers, professionals and technical experts working in the fields of Biomedical Signal processing (BSP) including applications, filtering and registration techniques, reconstruction and normalization algorithms, technical experts requiring an understanding of processing and analyzing biomedical signals, as well as postgraduate students working on image processing and novel signal processing paradigms applied to BSP.