Bentham Science Publishers

The advent of large-scale production and clinical trials of drugs developed through diverse production routes - involving viruses, microbes, plants, and animals - has increased the demand for an expanded capacity for pharmaceutical manufacturing. The production and purification of expressed proteins accounts for the bulk of the manufacturing costs for new therapeutics. Several pharmaceutical proteins have been synthesized by exploiting plant genetics allowing producers to override conventional approaches used to manufacture pharmaceuticals. The process of inserting a gene into a host organism for the purpose of harvesting a bioactive molecule for therapeutic use is known as molecular pharming.

Frontiers in Molecular Pharming covers an array of topics relevant to understanding the structure, function, regulation, and mechanisms of action, biochemical significance, and usage of proteins and peptides as biomarkers, therapeutics, and vaccines for animals and humans. The contributions aim to highlight current progress in three areas, including system biology (in vivo characterization of proteins and peptides), molecular pharming for animals and molecular pharming for humans. The book gives special attention to computational biology tools, production platforms and fields (such as immunoinformatics) and applications of molecular pharming (such as veterinary therapeutics). A balance of theoretical concepts and practical applications is provided through 13 chapters.

Frontiers in Molecular Pharming is an invaluable resource for students and researchers of biochemistry, molecular biology, and biotechnology. The book also serves as a springboard for understanding the process of how discoveries in protein and peptide research and its applications are coming to fruition.

Biosensing technology is rapidly flourishing in recent years due to the advancement of bio-MEMS/NEMS. However, the booming development of biosensors has not been very well addressed to the unmet clinical needs. Advances in Biosensing Technology for Medical Diagnosis initiates a headway into the realm of cutting-edge diagnostic tools which are expected to become routine clinical practice. This book aims to broaden the readers' horizon and guide them in tailoring different biosensing techniques for specific diagnostic procedures.

Key Features:

- 12 chapters cover several aspects of biosensing technologies including working principles and clinical validations

- highlights the state-of-the-art biosensing technology developed in all fields

- provides information about specific applications of novel biosensors used in clinical diagnosis,

- provides step-by-step guidance of microfabrication for biosensors

- focuses on bridging the gap between the scientific and the clinical communities

- provides information about the diagnostic applications of biosensors for different diseases (including infectious diseases and neurodegenerative diseases).

- covers Information about unconventional nano/microfluidic biosensor systems

- features contributions from renowned experts in the field of biomedical engineering

Advances in Biosensing Technology for Medical Diagnosis serves as a reference for healthcare providers and biomedical engineers who are interesting in biosensing techniques in medicine. The information provided in this reference will also benefit healthcare policymakers who are interested in new technologies that can impact the delivery of diagnostic services in healthcare systems.

"Frontiers in Natural Product Chemistry" is an Ebook series devoted to publishing the latest and most important advances in natural product chemistry. The Ebook series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds including coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussion of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of new methods are included. Chosen eminent scientists write contributions and each volume are devoted to major advances in natural product chemistry. Topics include the isolation, structure, biosynthesis, biological activity, and chemistry of the major groups of natural products such as alkaloids, terpenoids, steroids, aliphatic, aromatic and O-heterocyclic compounds, and other metabolites of plant, marine and microbial origins, developments in enzymology, nucleic acids, genetics, chemical ecology, primary and secondary metabolism, isolation and analytical techniques, and other areas which will be of general interest to all workers in the area. "Frontiers in Natural Product Chemistry" is essential for all scientists involved in natural product chemistry who wish to keep abreast of rapid and important developments in the field.

Frontiers in Natural Product Chemistry is a book series devoted to important advances in natural product chemistry. The series features volumes that cover all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.

Volume 11 of the series brings together 5 reviews:

- Medicinal importance of turmeric (curcuma longa) and its natural products

- Novel natural compounds for hepatocellular carcinoma treatment

- Herbal drug substitution (abhava-pratinidhi dravya): a key to stopping economic adulteration of botanical ingredients

- Synthetic and natural agents as bacterial biofilm inhibitors

- Quercetin chemistry, structural modifications, SAR studies and therapeutic applications: an update

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds including coverage of work on natural substances of land and sea and of plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are included.

The third volume of the series brings seven reviews covering natural products from marine plant sources, natural oligosaccharides, topical sesquiterpenes for pain treatment, biological activity of piperidinols and much more.

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.

The fifth volume of the series brings six reviews covering these topics:

-Inhibition of monoamine oxidase (MAO) via green tea extracts

-Sesquiterpene lactone cynaropicrin as novel inhibitor of Bcr-Abl fusion oncogene expression

-Effects of dietary polyphenols on chronic diseases

-Overview of past and present developments towards biotechnological and molecular approaches to improve taxol production

-Cytotoxicity through molecular targets involved in apoptosis

-Health related enzyme inhibiting natural products from medicinal plants

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.

Volume seven of the series brings seven reviews covering these topics:

- Plant-Derived Anticancer Compounds Used in Cancer Therapies

- Pradimicin and Benanomicin Antibiotics

- The Chemical Compositions of Bixa orellana and their Pharmacological Activities

- Overview of Phytochemistry and Pharmacology of Nilakanthi (Ajuga bracteosa Wall. ex Benth.)

- Tetracyclic benzocarbazoles and derivatives

- Chalcones as Antiinflammatory, Antidiabetic, and Antidepressant Agents

- Bioactive Steroids from Marine Organisms

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.

Volume nine of the series brings together 7 reviews on a variety of natural products and sources along with a chapter on the basics of investigating antioxidant activity.

Propolis and its key chemical constituents: a promising natural product in therapeutic applications

Investigation of the effects of using omega-3 fatty acids on egg quality in functional egg production

Quercetin, a flavonoid with remarkable anticancer activity

Swertiamarin for the treatment of metabolic syndrome

Overview of traditional uses, phytochemistry and pharmacology of Peganum harmala l.

Investigation of measurement methods of antioxidant activity and involved mechanisms

Recent progress on natural and synthetic flavanone and its derivatives

Role of virgin coconut oil as a multiple health promoting functional oil

Frontiers in Protein and Peptide Sciences is a book series focused on leading-edge research on the structure, physical properties, and functions of proteins and peptides. Authors of contributions in this series have updated their work with new experimental data and references following their initial research. Each volume highlights a number of important topics in current research in the field of protein and peptide chemistry and molecular biology, including membrane proteins and their interactions with ligands, computational methods, and proteins in disease and biotechnology. The series is essential reading for protein chemists and researchers seeking the latest information about protein and peptide research.

Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine.

This volume includes reviews on the following topics:

-the role of microvesicles and exosomes in mesenchymal stem cell (MSCs) in treating diseases while overcoming side effects

-alternative models for understanding cancer stem cell biology

-stem cells treatments for orthopaedic injury and endocrine disorders

-wound healing biomaterials

-theoretical models of hematopoietic cell dynamics (with implications for bone marrow transplants)