Bentham Science Publishers

This book presents research focused on the design of fractal antennas using bio-inspired computing techniques. The authors present designs for fractal antennas having desirable features like size reduction characteristics, enhanced gain, and improved bandwidths. The research is summarized in six chapters which highlight the important issues related to fractal antenna design and the mentioned computing techniques. Chapters demonstrate several applied concepts and techniques used in the process such as Artificial Neural Networks (ANNs), Genetic Algorithms (GAs), Particle Swarm Optimization (PSO) and Bacterial Foraging Optimization (BFO). The work aims to provide cost-effective and efficient solutions to the demand for compact antennas due to the increasing demand for reduced sizes of components in modern wireless communication devices.

A key feature of the book includes an extensive literature survey to understand the concept of fractal antennas, their features, and design approaches. Another key feature is the systematic approach to antenna design. The book explains how the IE3D software is used to simulate various fractal antennas, and how the results can be used to select a design. This is followed by ANN model development and testing for optimization, and an exploration of ANN ensemble models for the design of fractal antennas.

The bio-inspired computing techniques based on GA, PSO, and BFO are developed to find the optimal design of the proposed fractal antennas for the desired applications. The performance comparison of the given computing techniques is also explained to demonstrate how to select the best algorithm for a given bio-inspired design. Finally, the book explains how to evaluate antenna designs.

This book is a valuable resource for students (from UG to PG levels) and research scholars undertaking learning modules or projects on microstrip and patch antenna design in communications or electronics engineering courses.

This reference explores the science of signaling mechanisms associated with diseases like endocrine, metabolic, and immune disorders which are linked to oxidative stress-mediated disease mechanisms. The common diseases in these categories include diabetes mellitus and arthritis and conditions defined by inflammation and autoimmunity. These diseases involve metabolic pathways mediated by reactive oxygen species or free radicals. The pathways are targets in the mechanism of drugs that aim to treat related disorders. The book covers key topics in free radical biology that help to understand the nature of the pathways and the pharmacology of the drugs that are designed to target them.

5 chapters elucidate the free radical biology of the diseases.

1. Role of free radical biology in diabetes mellitus

2. Role of GSK3 in the regulation of insulin release and glucose metabolism

3. Regulatory role of NRF2 in rheumatoid arthritis

4. Role of free radical biology in Alzheimer's disease

5. Regulatory role of immune cells mediated antibody on rheumatoid arthritis Key features:

- Elucidates the key biochemical and pharmacological mechanisms that are mediated by free radicals in common endocrine, metabolic and immune diseases

- Explains the activation of immunological factors (like RF and ACPA) that trigger inflammation and arthritis

- Covers the role of free radicals in Alzheimer's disease and new interventions that target mitochondrial mechanisms

- Systematically explains the molecular biology of free radicals with the help of schematic diagrams

- Includes references for further reading The accessible and structured text in this reference makes it a suitable resource for all biomedical scientists, faculty, and postgraduate students in academia and industry.

Positioned at the crossroads of genomics, proteomics, artificial intelligence, and biomedical engineering, this book provides a roadmap for leveraging computational intelligence to address the complex challenges of modern life sciences, healthcare, and industrial biotechnology.

Across twelve comprehensive chapters, the book lays the foundations for sequencing technologies, omics data, and the principles of biotechnology data management. It then transitions into the application of machine learning models ranging from neural networks to optimization frameworks to extract meaningful insights from large-scale biological datasets. Subsequently it addresses pressing challenges such as data noise, scalability, and ethical AI, while also highlighting algorithmic breakthroughs in pharmacogenomics, drug discovery, precision medicine, and synthetic biology. Case studies illustrate real-world applications, from CRISPR diagnostics and clinical trial optimization to agricultural genomics and biomedical engineering innovations. The closing chapters project the future trajectory of biotechnology, exploring quantum computing, federated learning, and secure data-sharing techniques.

Key Features:

Uncovers the revolutionary role of computational algorithms in biotechnology research and healthcare

Explores the integration of AI, ML, and optimization methods in genomics, proteomics, and systems biology

Analyzes real-world applications through case studies in pharmacogenomics, CRISPR, and agritech

Provides practical insights into implementing secure, scalable, and ethical data solutions

Gives an understanding future trends such as quantum computing and federated learning in biotech innovation.

Some arrangements and structures of permanent magnets are hypothesized to exert measurable physiological and pathological effects on living tissues when exposed to the resultant electromagnetic field. From Microbe to Man: Biological responses to artificial static magnetic field-exposure explores the effects of such arrangements based on this hypothesis.

The book begins with an explanation of the mechanisms of artificial static magnetic fields (SMFs). This is followed by sequential sections presenting the effects of SMF exposure on living organisms backed by thorough experimental studies (on microbial, animal and human trials). In conclusion, the work reveals the positive nature of SMF treatment and shows that this is indeed a viable alternative to invasive treatment in the case of a number of both acute and chronic conditions, such as stomatological pain and osteoporosis.

From Microbe to Man: Biological responses to artificial static magnetic field-exposure is aimed chiefly at medical professionals and the research community studying alternatives to conventional pain medicine and physiotherapy. However, laypeople interested in non-invasive medical treatment options can also benefit from the easy-to-read layout of the contents of this volume.

Dramatic developments in developing semiconductor device technology and nanotechnologies over the last decades has placed increasing demands on the fabrication and design of new electronic devices, It is now necessary to implement nanoscale gate geometries to achieve the highest performance standards in new devices. The need to understand and model the operation of nano-devices is, therefore, fundamental to future development and optimal design.

From Semiclassical Semiconductors to Novel Spintronic Devices explains research related to new spintronic devices. This E-book: reports unique results on fabrication and the quite uncommon performance of Si-based solar cells with novel contacts chemically deposited on traditionally prepared semiconductor parts of the solar cell, details the mechanism behind efficient solar radiation conversion and the thermodynamics involved in theory and practice, discusses photonic condensate and relic radiation - exotic topics for theoretical astrophysics which also present possible power tools for achieving highly efficient energy conversion.

This e-book is a useful review on the latest achievements in spintronic technology, characterization methods and nanoscaled active elements modeling for novel device design and applications The text within this e-book serves as a handy resource for graduate and PhD students as well as for professionals interested in the field of semiconductor device technology and modeling as well as spintronics.

"Frontiers in Anti-Cancer Drug Discovery" is an eBook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest advances in anti-cancer drug design and discovery. In each volume, eminent scientists contribute reviews relevant to all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

The eleventh volume of the series focuses on reviews on targeted therapies and drug delivery systems. This volume covers the following topics:

- PI3K/Akt/mTOR Pathway in Acute Lymphoblastic Leukemia Targeted Therapies

>- Polymeric Nanomedicines in Treatment of Breast Cancer: Review of Contemporary Research

>- Treatment of Lung Cancer in the New Era

>- Oral Administration of Cancer Chemotherapeutics Exploiting Self-Nanoemulsifying Drug Delivery System: Recent Progress and Application

>- Targeting Approaches for the Diagnosis and Treatment of Cancer

Frontiers in Anti-Cancer Drug Discovery is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Frontiers in Anti-Cancer Drug Discovery is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery, including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The Ebook series is essential reading for all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Frontiers in Anti-Cancer Drug Discovery is an eBook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

The sixth volume of the series features chapters on several topics including:

- Monocarboxylate transporters as anti-cancer drug targets

- Interferon α-2b treatment for hepatocellular carcinoma

- Anthracyclines in cancer therapy

- Magnetosomes and tumor therapy

…and more.

Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest and the most important advances in anti-cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. Each volume is devoted to the major advances in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

The eighth volume of the series features chapters covering the following topics:

- T cells in gastrointestinal cancers

- The pharmacology of adjudin – a male contraceptive with anti-cancer properties

- Manipulating the tumor microenvironment

- Treatment of hepatocellular carcinoma

- Gold-based compounds as potential anti-cancer drug candidates

- Oral nanostructure drug delivery for anti-cancer treatment

Anti-infective agents are a distinct class of pharmacologically important molecules that has served mankind in different capacities to combat life-threating pathologic conditions. They include antibacterial, antifungal, antiviral, antituberculosis, antimalarial and urinary anti-infective agents. However, evolutionary changes, adaptations and development of pathogenic microorganisms strains the therapeutic efficacy of these drugs thus limiting their clinical utility over the years.

Frontiers in Anti-Infective Agents Volume 5 is a collection of notable research efforts, successful anti-infective drug development programmes and a comprehensive overview of the successes and failures of recent clinical trials in this domain. The volume covers interesting topics: 1) the treatment of acute wounds with the vikut® formula, 2) anti-infective treatment of ocular diseases and 3) sars-cov vaccine development and antimicrobial therapy for SARS symptoms. A chapter summarizing recent anti-infective approaches rounds up the contents of this volume.

This volume is a timely reference for postgraduate scholars and researchers seeking updates in specific areas of anti-infective drug development. Allied healthcare professionals (clinical and public healthcare professionals) can also benefit from the information presented within.

Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.

The tenth volume of this series features 4 reviews on the following topics:

-Pharmacotherapy of Posterior Segment Ocular Infections

-Discovery and Development of Antimalarial Drug-Resistance Reversal Agents

-Omics Technologies and Anti-Infective Drug Discovery

-Possible Cutaneous Adverse Effects of Anti-Infective Vaccinations

This eBook series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the eBook series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.

The fifth volume of this series features 6 chapters that cover the following topics:

- Virus infection pathways in living cells

- Antimicrobial activity of natural products (essential oils and food products)

- Medicinal plants that produce immunomodulators of veterinary interest

- In silico approaches for determination of drug targets

This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships.

Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.

The seventh volume of this series features 7 chapters that cover the following topics:

- Gut micriobiota and gastrointestinal cancer

- Dengue virus infections

- Synergistic antibiotic drug interactions

- Molecular modeling of antibacterial drugs

- Nucleic acid aptamers as anti-infective agents

- Fungal multidrug resistance

- The role of hydrogen sulfide in infections

This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships.

Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.

The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively.

- Use of preclinical and early clinical data for accelerating antimicrobial drug development

- Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs

- Scope and limitations on the potent antimicrobial activities of hydrazone derivatives

- Current scenario of anti-leishmanial drugs and treatment

- Dengue hemorrhagic fever: the potential repurposing drugs

"Frontiers in Anti-Infective Drug Discovery" is an eBook series devoted to publishing the latest and the most important advances in Anti-Infective drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Infective drug design and discovery. Each volume is devoted to the major advances in Anti-Infective drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

This ebook series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the ebook series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships.

Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.

The third volume of this series features 6 chapters that cover a variety of topics including:

- Drug Discovery for TB

- Therapeutic Limitations due to Antibiotic Drug Resistance

- Applications for Virus Vaccine Vectors in Infectious Disease Research

- NewCastle Disease Virus

- Anti-Infective Therapy Against Leishmaniasis

- Anti-Viral Activity of Proanthocyanidins

"Frontiers in CNS Drug Discovery" is an eBook series devoted to publishing the latest and the most important advances in Central Nervous System (CNS) drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in CNS drug design and discovery. Each volume is devoted to the major advances in CNS drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

"Frontiers in Cardiovascular Drug Discovery" is an eBook series devoted to publishing the latest and the most important advances in Cardiovascular drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in cardiovascular drug design and discovery. Each volume is devoted to the major advances in cardiovascular drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Frontiers in Cardiovascular Drug Discovery is an eBook series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The eBook series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology.

The third volume of the series covers the following topics:

- P2Y12 receptor agonists

-Heart failure pharmacotherapy

-Vasopressin and the cardiovascular system

-Cerebral small vessel disease

-Complement blocking therapeutic strategies

-New antiplatelet and anticoagulating agents for gastrointestinal treatments

Frontiers in Cardiovascular Drug Discovery is a book series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The book series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology.

The fifth volume of the series covers the following topics:

-The Lipid Hypothesis: From Resins to Proprotein Convertase Subtilisin/Kexin Type-9 Inhibitors

-The Role of SGLT2i in the Prevention and Treatment of Heart Failure

-Natural Products and Semi-Synthetic Compounds as Antithrombotics: A Review of the Last Ten Years (2009-2019)

-Transient Receptor Potential Channels: Therapeutic Targets for Cardiometabolic Diseases?

-Treatment of Raynaud’s Phenomenon

-Traditional Medicine Based Cardiovascular Therapeutics

-Cardiovascular Disease: A Systems Biology Approach

Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders.

Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimers Disease research.

Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders.

Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimers Disease research.

The third volume of this series features research on

-perfusional modifications in prodromal Alzheimer's disease,

-BACE inhibition treatment,

-frontotemporal dementia caused by progranulin mutations

-evidence-based treatment for psychological symptoms of Alzheimer’s Disease

Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series which covers recent topics related to understanding Alzheimer's disease (AD) that causes dementia and has a neurodegenerative effect on the brain. The disease affects memory, thought process, and language of affected individuals. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders.

Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimer’s Disease research.

The fifth volume of this series features chapters covering critical discussions on AD management and new therapies. The topics reviewed in this volume include:

- Current concepts in management of AD

- The amyloid cascade hypothesis and stem cell-based AD therapy

- Phytochemicals targeting AD

- Dementia screening in primary clinical care settings

- Updates in dementia / AD clinical research and drug development