Bentham Science Publishers

Mitochondria are multifunctional organelles that actively participate in the immune-inflammatory response in various pathologies. This volume updates readers on knowledge about mitochondria function. The editors have compiled six chapters about inflammation in its broadest sense, with contributions from active groups of cell biologists, infectologists and pathologists.

The chapters in this volume focus on research related to five notable diseases:

(1) two diseases (one bacterial and one viral) in which the exacerbation of the inflammatory response can lead to neuropathies: leprosy (one of the oldest diseases in the world) and Zika fever (a disease relatively new in Brazil)

(2) three diseases (two bacterial and one viral) in which the exacerbation of the inflammatory response can lead to irreversible lung damage that can cause rapid death: tuberculosis, pneumonia and the most recent global disease, COVID- 19.

New information about mitochondrial biology is presented, such as the effect of aerobic physical exercise as a stimulator for mitochondria multiplication, and the role of mitochondrial damage in inducing immune-inflammatory responses to pathogens. The contents shed light on mitochondrial biochemical pathways that could serve as potential therapeutic targets.

This is an important reference for scholars (cell biologists, microbiologists) in universities, hospitals and scientific research centers working on biological and biomedical problems, and for health professionals involved in infection control.

This book focuses on recent developments in integrating AI, machine learning methods, medical image processing, advanced network security, and advanced antenna design techniques to implement practical Mobile Health (M-Health) systems. The editors bring together researchers and practitioners who address several developments in the field of M-Health. Chapters highlight intelligent healthcare IoT and Machine Learning based systems for personalized healthcare delivery and remote monitoring applications. The contents also explain medical applications of computing technologies such as Wireless Body Area Networks (WBANs), wearable sensors, multi-factor authentication, and cloud computing. The book is intended as a handy resource for undergraduate and graduate biomedical engineering students and mobile technology researchers who want to know about the recent trends in mobile health technology.

This eBook covers the application of high-throughput R&D to both fundamental and applied catalysis including catalyst synthesis, characterization, and testing in various reactor types. Chapters include topics such as applications ranging from optimizations of established industrial catalysts to the discovery of innovative new materials, examples of the development of innovative parallel characterization methods, and cases of real catalyst testing in small scale reactor systems. Readers will also find chapters that cover commodity chemicals produced using continuous gas phase processes as well as fine chemicals produced in liquid phase batch reactors. The potential of industrial chemicals production from biorenewable feedstocks is also presented. The steadily improving high throughput workflows are today being applied to relevant reactions and targets such as hydrotreating, Deacon oxidation, Fischer-Tropsch, propane dehydrogenation, C4 oxidation, methane coupling, exhaust gas catalysis, bio-based Nylon, fuel cells and vitamins. The topics presented in this eBook have been contributed by researchers from academia as well as industry, making this eBook a well-balanced reference, which could be of particular interest to professional, industrial or service R&D labs.

His text book serves as a guide for readers learning about the technical design of intelligent instruments, that is, instruments designed to collect information about the performance of other electronic devices and systems. The book introduces the readers to the concept of intelligent instrumentation and guides them on more advanced aspects of the subject including signal detection and analysis, data processing, performance analysis and data communication. Practical examples are also provided in the latter half of the book to blend the theoretical concepts with applied knowledge for the benefit of the reader.

Key features:

- Features 10 chapters covering key topics related to intelligent instrument design and operation

- Provides theoretical knowledge of fundamental concepts

- Provides practical examples of working instrument models (online equipment monitoring system and a mobile robot)

- Provides notes on the use of packages such as MATLAB, ARGUINO and Proteus to develop intelligent instruments

- Presents information in a simple, easy-to-understand format which is reader friendly

- Presents handy chapter notes and references for the reader

Modern Intelligent Instruments - Theory and Application is a useful textbook for engineering students and technical apprentices learning about instrumentation and PCB design and testing.

This comprehensive book covers spectral analysis theory for radio signals and innovative devices designed for filtering electromagnetic waves across diverse frequency ranges. The book features 14 chapters that explain the working of devices utilizing surface and bulk acoustic waves. The chapters provide insights into acousto-optical and acousto-electronic Fourier processors' design principles, description methods, and characteristics. The inclusion of algorithms for multi-channel frequency discriminators enhances the precision of radio signal frequency measurements, ensuring stability in tracking frequency meters amidst intense interference. The book also includes mathematical modeling and experimental studies of waveguide microwave filters and X-band multiplexers, specifically tailored for non-pressurized radio electronic equipment in space communication systems. Notably, the book introduces readers to a compelling alternative to conventional filters: 2-D periodic structures in the form of thin perforated metal meshes that offer compact solutions for millimeter and sub-millimeter wave systems. A significant portion of the book is dedicated to the development of highly selective microstrip filters, incorporating complex topological structures with limited resonators and numerous couplings. This approach allows for the formation of numerous attenuation poles at finite frequencies, facilitating the achievement of high electrical parameters and compact filter sizes. Engineers and scientists specializing in communication systems design and analog Fourier processors will find a wealth of well-established and original solutions within this book.

Neurodegenerative diseases are a complex heterogeneous group of diseases associated with site-specific premature and slow death of certain neuronal populations in brain and spinal cord tissues. For example, in Alzheimer disease, neuronal degeneration occurs in the nucleus basalis, whereas in Parkinson disease, neurons in the substantia nigra die. The most severely affected neurons in Huntington disease are striatal medium spiny neurons. The neuronal populations that are lost in neurodegenerative diseases modulate functions such as controlling movements, processing sensory information, memory, and making decisions. Although, the molecular mechanism of neurodegeneration remains unknown, but excitotoxicity, inflammation, and oxidative stress may contribute to neural cell demise independently or synergistically. The purpose of this E-book is to present readers with cutting edge and comprehensive information on molecular aspects of neurodegenerative diseases and neuroprotection in a manner that is useful not only to students and teachers, but also to researchers and physicians.

This volume of Frontiers in Heart Failure comprehensively covers the gap between clinical management of heart failure and advanced molecular imaging techniques (SPECT, PET, MRI etc.). These techniques provide valuable evidence to cardiologists for the evaluation and follow-up of heart failure patients. It brings forth established research data regarding the pathophysiology, clinical presentations and therapy of heart failure, in a balance between clinical items and molecular imaging modalities. Readers will also find additional chapters on hybrid cardiovascular imaging techniques as well as guidelines on imaging artifacts and radiation protection. This volume is a useful resource for radiologists, cardiologists, cardiac care nurses and medical physicists.

Cancer is one of the major causes of death worldwide. Despite hundreds of clinical trials currently in progress for cancer patients, the success rate is still very low. Understanding the molecular aspects of cancer development, the discovery of new molecular targets and rational drug design on this molecular basis should help in discovering early cancer biomarkers as well as novel therapeutic drugs.

This book describes various cancer topics on a molecular level and integrates information on the relationship between causes of cancer, cancer cell biology, metastasis, cancer prevention and drug design. This book should prove to be an extraordinary reference text for students, physicians and oncologists.

Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early-stage diagnosis.

Molecular Targets and Cancer presents information about cancer diagnosis and therapy in a simple way. It covers several aspects of the topic with updated information on par with medical board levels. The book features contributions from experts and includes an overview of cancer from basic biology and pathology, classifications, surveillance, prevention, diagnosis, types of cancer, treatment and prognosis.

The second part of this book discusses specialized topics in clinical oncology which include the pathophysiology of various types of cancer, cancer screening, different types of cancer surgery, cancer stem cell-targeted immunotherapy, nanotechnology for precision medicine applications in cancer and cancer surveillance.

This comprehensive guide is a valuable resource for oncologists, researchers, and all medical professionals who work in cancer care and research.

Molecular and Physiological Insights into Plant Stress Tolerance and Applications in Agriculture is an edited volume that presents research on plant stress responses at both molecular and physiological levels. Key Features: - Emphasizes the morphological and physiological reactions of plants and the underlying molecular mechanisms when faced with stress from environmental or pathogenic factors. - Explores microbial dynamics within the plant rhizosphere and the application of plant growth-promoting bacteria as biofertilizers and endophytes as biocontrol agents to enhance crop growth and productivity for sustainable agriculture. - Systematically summarizes molecular mechanisms in plant stress tolerance and discusses the current applications of biotechnology, nanotechnology, and precision breeding to obtain stress-tolerant crops, contributing to climate-smart agriculture and global food security. - Includes contributions and references from multidisciplinary experts in plant stress physiology, plant molecular biology, plant biotechnology, agronomy, agriculture, nanotechnology, and environmental science. The content of the book is aimed at addressing UN SDG goals 2, 12, and 15 to achieve zero hunger and responsible consumption and production, and to sustainable use of terrestrial ecosystems, respectively. This comprehensive resource is suitable for researchers, students, teachers, agriculturists, and readers in plant science, and allied disciplines.