Bentham Science Publishers

The world faces significant challenges as the population and consumption continue to grow while fossil fuels and other raw materials are depleted at ever-increasing rates. Environmental consciousness and a penchant for thinking about material cycles have caught on with consumers. Therefore, the use of environmentally compatible materials and sustainable production methods are now desired. Materials and Technologies for a Green Environment discusses the major issues surrounding the production of energy through biofuels and waste management. It comprises seven chapters that cover various fields of interest to readers involved in environmental management and sustainability planning. The topics covered include renewable energy sources, thermoelectric generators, electric vehicles, biodiesel production from poultry waste, scramjet combustion engines, and sustainable architecture for green buildings. Given its scope, this book is a valuable resource for students, researchers and engineers in environmental science, mechanical engineering, and chemical engineering and sustainability studies.

This book focuses on cases and studies of interest to mechanical engineers and industrial technicians. The considered applications in this volume are widely used in several industrial fields particularly in the automotive and aviation industries. Readers will understand the theory and techniques which are used in each application covered in each chapter.

The book contents include the following topics:

Numerical analysis of hydrokinetic turbines

Computational fluid dynamics of a CuO based nanofluid in mini-channel cross-sections

Orthodontic biomechanics of a NiTi arch wires

Reynold's number effects on fluid flow through Savonius rotors

Effect of operating parameters on Zn-Mn alloys deposited from additive-free chloride bath

Optical properties and stability of a blue-emitting phosphor (Sr2P2O7:Eu2+) Under UV and VUV excitation

Numerical study of the influence of nanofluid type on thermal improvement in a three dimensional mini channel

Electrochemical studies and characterization of Zn-Mn coatings deposited in the presence of novel organic additives

Prediction of fire and smoke propagation under a range of external conditions

Structural design of a 10 kW H-Darrieus wind turbine

The presented case studies and development approaches aim to provide the readers, such as graduate students, PhD candidates and professionals with basic and applied information broadly related to mechanical engineering and technology.

This book focuses on cases and studies of interest to mechanical engineers and industrial technicians. The considered applications in this volume are widely used in several industrial fields particularly in the automotive and aviation industries. Readers will understand the theory and techniques which are used in each application covered in each chapter.

Volume 3 includes the following topics:

Numerical simulations of three-dimensional laminar mixed convection heat transfer of water-based-Al2O3 nanofluid in an open cubic cavity with a heated block.

Nonlinear formulations of Element-Free Galerkin Method (EFGM) for large deformation analysis of Ogden's hyperelastic materials, emphasizing incompressibility and mesh distortion avoidance.

Development of a 3D numerical model with LS-DYNA using a coupled SPH-FEM method to simulate hydraulic behavior of a Ski-Jump Spillway with dentates, showcasing precision through validation.

Exploration of enhancing the inlet system of an LPG-H2 fueled engine using a static inclined blade turbine, analyzed through Computational Fluid Dynamics (CFD) simulations.

Effective utilization of Artificial Neural Networks (ANN) in heat transfer applications, addressing issues like fouling in heat exchangers, showcasing their accuracy compared to experimental data.

Investigation of the impact of nitrogen concentration on the structure and properties of ZrN coatings deposited by magnetron sputtering, evaluating variations in structural and mechanical properties.

Forced convection in a horizontal cylindrical pipe with pseudoplastic fluid, considering uniform constant heat flux and uniform temperature as boundary conditions.

Modeling and experimental study of a water solar collector coupled to an optimized solar still, aiming to enhance freshwater production in a solar distillation system under specific climatic conditions.

Exploration of the effect of film thickness on the structure and properties of Ti-N films deposited by magnetron sputtering, utilizing theoretical and experimental analysis to confirm the rock salt TiN structure.

The presented case studies and development approaches aim to provide readers with basic and applied information broadly related to mechanical engineering and technology.

Present day mechatronic systems are designed with synergistic integration of mechanics, electronics and computer technology to produce intelligent devices for the purpose of solving real-world problems. Crucial requirements for a mechatronic system are robustness and fault tolerance, i.e. it should have the ability to process incomplete, imprecise or uncertain information. Such systems often have to work in collaborative environments while being subjected to adverse conditions yet adhering to strict safety standards. This e-book explains the fundamentals of designing such systems from the first principles and how to embed intelligence into them. Examples in this volume are not restricted to production lines, but extend to extreme safety based systems such as space and underwater robotics, autonomous transportation systems, aviation systems and medical robots. Moreover, this e-book also presents recent developments in the design of innovative and intelligent mechatronic systems, applied to robotics and transportation systems, thereby providing an authoritative support for researchers and professionals having basic knowledge in mechatronics.

Beta-glucan is a polysaccharide and an important food supplement that strengthens the immune system. Beta-glucan can be obtained from many food sources such as mushrooms, yeast, or oats. Beta-glucan has a therapeutic use in the treatment of many diseases, thanks to its immune system strengthening effect. Its use helps curtail the need for administering high levels of antibiotics in case of serious infections.

This book presents information about the medical applications of beta-glucan. Starting with an introduction to the basic biochemistry and classification of beta-glucan, the contents explain the readers about its use in treating a variety of medical conditions. These include cancer, allergies, COVID-19, respiratory tract infections, hypercholesterolemia, diabetes and many other other endocrinological, immunological and infectious diseases.

This book is a comprehensive resource about the medical use of beta-glucan where any reader can find topical information and learn about recent studies on the therapeutic effects of beta-glucan on the treatment of different diseases.

Medicinal Chemistry - Fusion of Traditional and Western Medicine is a textbook intended for students taking courses in the various fields of medicinal chemistry, pharmacy, medical and dental programs. Moreover, people working in the pharmaceutical industry and doctors preparing for Medical Board Exams will also find it useful. Since, new drugs are being developed by multi-disciplinary teams; this E-Book describes new paradigms that are emerging in modern biology, biochemistry and medicine. It is therefore a fusion of traditional and western medicine and between systems thinking and reductionist thinking. Readers will learn about how new drugs are investigated, developed and eventually approved by the FDA. The book also includes important information about cGMP, GLP and the FDA regulatory requirements, the importance of environmental toxins, such as bisphenol A (BPA) and perfluorooctanoic acid (PFOAA) in autoimmune diseases and health. This book offers exceptional value in its descriptions of RNA, epigenetics, toxicology, new drug development, genetically modified organisms and analytical chemistry that cannot be found in other textbooks.

Medicinal Chemistry - Fusion of Traditional and Western Medicine is a textbook intended for students taking courses in the various fields of medicinal chemistry, pharmacy, medical and dental programs. Moreover, people working in the pharmaceutical industry and doctors preparing for Medical Board Exams will also find it useful. Since, new drugs are being developed by multi-disciplinary teams; this E-Book describes new paradigms that are emerging in modern biology, biochemistry and medicine. It is therefore a fusion of traditional and western medicine and between systems thinking and reductionist thinking.

The 3rd edition attempts to explain the predictive, preventive, personalized and participatory (P4) paradigm of medicinal chemistry. This edition features new chapters focusing on personalized medicinal chemistry and the endocrine system (with a discussion of bioidentical hormone therapy). Other chapters cover the disease mechanism and associated pharmacology of drugs for several diseases including cancer, metabolic syndrome, diabetes, heart disease, stroke, osteoporosis, neurodegenerative diseases, the immune system and much more. The new edition also includes an overview of emergent medical problems and possible solutions (such as the flu, ebola virus, global climate change, a shortage of medicines, genetic engineering and stem cell therapy). Drugs that have been approved by the FDA since the 1st edition was written are also included. The book concludes with an explanation of systems thinking in medicinal chemistry, an important, yet rarely explored topic in other medicinal chemistry text books.

The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of chemical basis of drug action. This first volume of the series is comprised of 8 chapters focusing on basic background information about medicinal chemistry. It takes a succinct and conceptual approach to introducing important fundamental concepts required for a clear understanding of various facets of pharmacotherapeutic agents, drug metabolism and important biosynthetic pathways that are relevant to drug action. Notable topics covered in this first volume include the scope and importance of medicinal chemistry in pharmacy education, a comprehensive discussion of the organic functional groups present in drugs, and information about four major types of biomolecules (proteins, carbohydrates, lipids, nucleic acids) and key heterocyclic ring systems. The concepts of acid-base chemistry and salt formation, and their applications to the drug action and design follow thereafter. These include concepts of solubility and lipid-water partition coefficient (LWPC), isosterism, stereochemical properties, mechanisms of drug action, drug receptor interactions critical for pharmacological responses of drugs, and much more. Students and teachers will be able to integrate the knowledge presented in the book and apply medicinal chemistry concepts to understand the pharmacodynamics and pharmacokinetics of therapeutic agents in the body.

The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of the chemical basis of drug action. Medicinal Chemistry of Drugs Affecting the Nervous System is the second volume of the series and it presents 8 chapters focusing on a comprehensive account of drugs affecting the nervous system. The volume informs readers about the medicinal chemistry of relevant drugs, which includes the mechanism of drug action, detail structure activity relationships and metabolism as well as clinical significance of drugs affecting autonomic and central nervous system. Chapters in this volume cover cholinergic drugs, adrenergic drugs, antipsychotics, antidepressants, sedatives, hypnotics, anxiolytics, antiepileptic drugs, anesthetics and antiparkinsonian drugs, respectively. Students and teachers will be able to integrate the knowledge presented in the book and apply medicinal chemistry concepts to understand the pharmacodynamics and pharmacokinetics of therapeutic agents in the body. The information offered by the book chapters will give readers a strong neuropharmacology knowledge base required for a practicing pharmacist.