Bentham Science Publishers

Fungal Lipid Biochemistry explores the intricate biochemistry of fungal and microbial lipids. The book focuses on recent advances in our knowledge about the distribution, classification, and biochemistry of fungal lipids. The book is divided into four sections, starting with an introduction to fungal lipids which includes definition, classification, nomenclature, and some historical aspects of fungal lipid research. This is followed by an overview of fungal lipids, and environmental and nutritional cultural conditions affecting lipid production. The second section contains four chapters that explain the metabolism of fatty acids, their biosynthetic pathways together with their storage mainly in the form of triacylglycerols. The latter includes a key description of the recently discovered lipid droplet acting as a highly specific cellular compartment for the storage of neutral lipids. The third section contains five chapters concerned with the relatively recent interpretation of other major lipid classes which include glycerophospholipids, sphingolipids, aliphatic hydrocarbons, sterols, carotenoids, and polyprenols and their occurrence and biosynthesis. The final section covers lipid metabolism during fungal development and sporulation. Key features - Extensive coverage of fungal lipid biochemistry, with a focus on recent knowledge - Includes chapters for specific lipid classes with notes on their metabolism - Gives knowledge about the role of lipids in fungal growth and development - Provides references for further reading This book is a comprehensive reference for academics, scientific researchers, and industrial scientists (in biotechnology, food science and nutritional health) who require information about fungal lipid composition and biochemistry.

This reference focuses on defined types of compounds which are of interest to readers who are motivated to explore basic information about new materials for advanced industrial applications. General and established synthetic methodologies for several compounds are explained giving a straightforward approaches for researchers who intend to pursue new projects in materials sciences, This book presents 9 chapters, covering phthalocyanines, polymethines, porphyrins, BODIPYs, dendrimers, carbon allotropes, organic frameworks, nanoparticles and future prospects. Each chapter covers detailed synthetic aspects of the most established preparation routes for the specific compounds, while giving a historical perspective, with selective information on actual and outstanding applications of each material, unraveling what likely might be the future for each category. This book is intended as a hands-on reference guide for undergraduates and graduates interested in industrial chemistry and materials science.

GIS - An Overview of Applications is a compilation of reviews that give an overview of the latest advances in Geographic Information System (GIS) technology. The multidisciplinary nature of the book gives readers perspectives in research fields as diverse as forest management, land use and cover, tourism, environment impact assessment, climate change studies, biodiversity and health care and mobility studies.

The book is a suitable reference for graduates involved in data engineering and GIS courses as well as working professionals in the field of data engineering, analysis and management.

Mucins are glycoproteins that are expressed in cells of different types and fulfill multiple functions that determine participation of these proteins in such processes as signal transduction, regulation of gene expression, cell proliferation, embryogenesis, cell differentiation, immunity, apoptosis and cancer development. This E-book series on mucins presents critical reviews on modern data concerning structures and functions of mucins, their roles in cell physiology and pathology as well as molecular aspects of therapy of mucin-associated diseases. Mucins are represented by two types of molecules: secreted mucins and membrane-bound (receptor) mucins. This e-book series represents a unique attempt to describe the molecular nature of mucin multifunctionality in separate volumes. Chapters in each volume demonstrate the central role of mucins as connectors and regulators of different signaling pathways and their participation metastatic processes. Clinical aspects of mucins, such as their role as diagnostic markers as well as possible applications in mucin-based immuno- and gene-therapies are also discussed.

This is the first volume of the series. This volume introduces readers to the general properties of mucins, followed by chapters on specific variants of gel-forming and soluble mucins. The volume concludes with information on the functions of secreted mucins.

This reference is a comprehensive review of genome editing in bacteria. The multi-part book meticulously consolidates research findings and insights on the applications of bacteria across several industries, including food processing and pharmaceutical development. The book covers four overarching themes for readers: a historical perspective of genome editing, genome editing in probiotics, applications of genome editing in agricultural microbiology and genetic engineering in environmental microbiology. The editors have also compiled chapters that provide an in-depth analysis of gene regulation and metabolic engineering through genome editing tools for specific bacteria.

Key topics in part 1:

- An Overview of advances in CRISPR-CAS research

- Applications of CRISPR/CAS9-based genome editing for industrial microorganisms

- Gut microbiome modulation to address gut dysbiosis

- Bifidobacterium genome editing for probiotic development and metabolic engineering.

- Insights into the use of lactic acid bacteria as starter cultures in the food

- Genome editing of vegetable-derived L. Plantarum

- Genome editing in Bacillus Licheniformis

Genome Editing in Bacteria is a definitive reference for scholars, researchers and industry professionals navigating the forefront of bacterial genomics.

This reference is a timely compilation of studies of genome size and genetic stability of regenerated plants. It presents 13 book chapters that cover recent advancements in CRISPR/Cas-based genome editing, the use of molecular markers to analyze somaclonal variation in tissue culture, and genetic stability assessment in various plant species, including medicinally valuable plants like Valeriana and Coffea. The book also highlights the role of flow cytometry in investigating polyploidy and provides valuable insights into genetic fidelity assessment of micropropagated woody plants and orchids. The contributors have shed light on the intra-specific and inter-specific genome and chromosome number variation with reference to gene duplication and DNA sequence loss. Molecular techniques for detecting ploidy levels and genetic homogeneity in regenerated plantlets are also discussed. Additional highlights of the book include brief guidelines for experimental protocols for flow cytometry and molecular markers, coverage of a wide range of plants, and supporting references. This is an excellent reference for biologists, geneticists, and plant scientists exploring genetic homogeneity and genome size variation in diverse plant groups.

Geriatric Anesthesia: A Practical Guide is a comprehensive reference on geriatric anesthesia. The book is divided into three sections. The first section covers the basics of both anatomical and physiological changes in senescence, and important polypharmacy considerations common in elderly patients. The next section covers anesthesia for cardiac and non-surgical patients. Various controversies and legal ethical issues that are particularly significant in the elderly such as advance directives, code status discussions, specific patient groups and shared decision-making prior to surgical interventions, are covered in the final section.

Key features

- 20 referenced chapters covering basic geriatric anesthesia considerations, cardiac and non-surgical patients and special topics, respectively

- Contributions and references from experienced anesthesiologists

- Emphasis on tailoring perioperative management depending on specific circumstances of patients

- Addresses novel and commonly overlooked topics related to the geriatric population

This book is a guide for both anesthesia providers and non-anesthesia medical providers, trainees and students. It equips them with necessary information to understand and devise anesthetic plans while being aware of postoperative complications and the respective treatment and management options.

Global Neutron Calculations provides assessment guidelines for nuclear reactors in a step-by-step manner. The book introduces readers to principal physical ideas, the fundamentals of nuclear reactors including the theory of self-sustaining chain reactions and the associated physical and mathematical calculations. The required theory, the mathematical appparatus and, the applied methods are comprehensively explained in the first half of the book followed by details about the applications of the theory and methods.

Readers will gain essential information about reactor control and surveillance, instrumentation and control, technology, fuel management, core design and the differences in reactor technologies.

Global Neutron Calculations demystifies technical and mathematical knowledge about reactor design, operation, safety and analysis for engineers learning about one of mankind’s most controversial means of power generation.

Glycals and Their Derivatives is an essential resource for understanding the emerging applications of carbohydrate-derived unsaturated sugars. Carbohydrates are versatile molecules, abundant in nature, biocompatible, and structurally diverse, with glycals and their derivatives showing remarkable biological activities, including antimicrobial and anticancer effects. It discusses the synthesis, transformations, and applications of glycals, offering valuable insights for researchers and professionals in glycoscience.

Key Features:

- Comprehensive Coverage: Explores the synthesis and transformation of glycals, glycosides), and 2-C-branched sugars, emphasizing their chemical and biological significance.

- Advanced Synthetic Strategies: Discusses recent advances, including metal-catalyzed and metal-free approaches for glycoside synthesis under mild conditions.

- Natural Product Synthesis: Highlights the total synthesis of medicinally important molecules derived from glycals.

- Cutting-Edge Applications: Examines the role of glycals in creating glycohybrids and glycoconjugates, opening avenues in glycobiology and glycotechnology.

Pharmaceutical manufacturing can be viewed as a supply chain which spans from the production and purchase of the starting and packaging materials through the manufacture of dosage forms until the safe reception of the finished product by the patient. The entire chain comprises of several processes: auditing, materials purchase (procurement), production, storage, distribution, quality control, and quality assurance.

The quality standard for pharmaceutical production is ‘current good manufacturing practice (CGMP)’‘, which is applied within the frame of a pharmaceutical quality system (PQS). This implementation, however, requires a scientific approach and has to take into account several elements such as risk assessment, life cycle, patient protection, among other factors. Hence, pharmaceutical manufacturing is a complex subject in terms of regulation, given the technical and managerial requirements. This comprehensive handbook describes CGMP for new professionals who want to understand and apply the elements which build up pharmaceutical quality assurance. The book gives details about basic quality control requirements (such as risk management, quality hazards and management systems, documentation, clean environments, personnel training) and gives guidelines on regulatory aspects. This is an ideal handbook for undergraduates studying pharmaceutical or industrial manufacturing and supply chains as well for entrepreneurs and quality control professionals seeking to learn about CGMP standards and implementing quality assurance systems in the pharmaceutical sector.