Application of Chirally Modified Nickel Catalysts for Production of Optically Active Compounds

The major patents concerning chirally modified nickel catalysts by enantiomerically pure tartaric acid are comprehensively surveyed. The methods of catalyst's preparation for attaining a high enantioselectivity and the synthetic routes for obtaining optically active compounds by using these tartaric acid-modified nickel catalysts are summarized. A recently claimed patent dealing with the robust chiral nickel catalyst, which exhibits an exceptionally high stability after preparation is also introduced.