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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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Interfacial Effects on the Conformation of Amyloid-Beta Peptide
- Source: Protein and Peptide Letters, Volume 16, Issue 2, Feb 2009, p. 182 - 188
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- 01 Feb 2009
Abstract
We examined the effects of air-water and water-sevoflurane interfaces on conformational properties of amyloid- β peptide (ABP). Fractions were extracted from sub-interfacial (air-water) and supra-interfacial (water-sevoflurane) layers and compared with aqueous bulk layers using fluorescence properties of ABP provided by a single tyrosine. The observations suggest that interfacial ABP may be more disordered than bulk ABP.
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