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2000
Volume 5, Issue 1
  • ISSN: 0250-6882
  • E-ISSN: 0250-6882
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Abstract

Background

Cardiomyopathies are a broad range of cardiac illnesses defined by mechanical and/or electrical dysfunction and abnormal ventricular hypertrophy or dilatation. Cardiomyopathies are classified into two categories: either primarily related to myocardial disease or secondary to other systemic or organ disorders, including the thyroid gland. Thyroid hormones have been linked to a wide range of significant effects on the cardiovascular system.

Case Presentation

We experienced a case of a 37-year-old male who presented with symptoms of heart failure and was discovered to have dilated cardiomyopathy. The echocardiography study revealed significant left ventricular global hypokinesia and severely depressed left ventricular systolic function. The laboratory testing confirms the presence of severe normocytic, normochromic anemia with severe hypothyroidism.

Conclusion

The present case illustrates that hypothyroidism should be addressed systematically by healthcare providers when dilated cardiomyopathy is identified, and thyroid function testing should be regularly performed.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2024-01-01
2025-09-30

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References

  1. MaronB.J. TowbinJ.A. ThieneG. AntzelevitchC. CorradoD. ArnettD. MossA.J. SeidmanC.E. YoungJ.B. Contemporary definitions and classification of the cardiomyopathies.Circulation2006113141807181610.1161/circulationaha.106.17428716567565
     [Google Scholar]
  2. SisakianH. Cardiomyopathies: Evolution of pathogenesis concepts and potential for new therapies.World J. Cardiol.20146647849410.4330/wjc.v6.i6.47824976920
     [Google Scholar]
  3. UdovcicM. PenaR.H. PathamB. TabatabaiL. KansaraA. Hypothyroidism and the heart.Methodist DeBakey Cardiovasc. J.2017132555910.14797/mdcj‑13‑2‑5528740582
     [Google Scholar]
  4. Bielecka-DabrowaA. GodoyB. SuzukiT. BanachM. von HaehlingS. Subclinical hypothyroidism and the development of heart failure: An overview of risk and effects on cardiac function.Clin. Res. Cardiol.2019108322523310.1007/s00392‑018‑1340‑130091084
     [Google Scholar]
  5. BiondiB. Mechanisms in endocrinology: Heart failure and thyroid dysfunction.Eur. J. Endocrinol.2012167560961810.1530/EJE‑12‑062722956554
     [Google Scholar]
  6. KleinI. DanziS. Thyroid disease and the heart.Circulation2007116151725173510.1161/circulationaha.106.67832617923583
     [Google Scholar]
  7. ZawadzkaK DziedzicR SurdackiA ChyrchelB. Thyroid hormones: An underestimated player in dilated cardiomyopathy?J. Clin. Med.20211016361810.3390/jcm10163618
     [Google Scholar]
  8. Abdel-MoneimA. GaberA.M. GoudaS. OsamaA. OthmanS.I. AllamG. Relationship of thyroid dysfunction with cardiovascular diseases: updated review on heart failure progression.Hormones202019330130910.1007/s42000‑020‑00208‑832488814
     [Google Scholar]
  9. BiondiB. CooperD.S. The clinical significance of subclinical thyroid dysfunction.Endocr. Rev.20082917613110.1210/er.2006‑004317991805
     [Google Scholar]
  10. DuntasL.H. ChiovatoL. Cardiovascular risk in patients with subclinical hypothyroidism.Eur. Endocrinol.201410215716010.17925/EE.2014.10.02.15729872482
     [Google Scholar]
  11. KaushikA AgrawalM. Relationship between subclinical hypothyroidism and the risk of cardiovascular complications.Cureus2023151e3370810.7759/cureus.33708
     [Google Scholar]
  12. ZúñigaD BalasubramanianS MehmoodKT Al-BaldawiS Zúñiga SalazarG Hypothyroidism and cardiovascular disease: A review.Cureus2024161e5251210.7759/cureus.5251238370998
     [Google Scholar]
  13. DorgalalehA. MahmoodiM. VarmaghaniB. Kiani NodeF. Saeeidi KiaO. AlizadehSh. TabibianSh. BamediT. MomeniM. AbbasianS. Kashani KhatibZ. Effect of thyroid dysfunctions on blood cell count and red blood cell indice.Iran. J. Ped. Hematol. Oncol.201332737724575274
     [Google Scholar]
  14. SolimanAT De SanctisV YassinM WagdyM SolimanN Chronic anemia and thyroid function.Acta. Bio. Medica.: Atenei. Parmensis.201788111912710.23750/abm.v88i1.6048
     [Google Scholar]
  15. Szczepanek-ParulskaE. HernikA. RuchałaM. Anemia in thyroid diseases.Polish Arch Internal Med2017127535236010.20452/pamw.398528400547
     [Google Scholar]
  16. CappolaA.R. DesaiA.S. MediciM. CooperL.S. EganD. SopkoG. FishmanG.I. GoldmanS. CooperD.S. MoraS. KudenchukP.J. HollenbergA.N. McDonaldC.L. LadensonP.W. CeliF.S. DillmanW. EllervikC. GerdesA.M. HoC. IervasiG. LermanA. MakinoA. OjamaaK. PeetersR. PingitoreA. RazviS. WassnerA.J. Thyroid and cardiovascular disease.Circulation2019139252892290910.1161/circulationaha.118.03685931081673
     [Google Scholar]
  17. WilsonS.A. StemL.A. BruehlmanR.D. Hypothyroidism: Diagnosis and treatment.Am. Fam. Physician20211031060561333983002
     [Google Scholar]
  18. DhirG. JainV. MerrittA. Thyroid disorders.Prim. Care202451340541510.1016/j.pop.2024.04.00139067967
     [Google Scholar]
  19. RastogiP. DuaA. AttriS. SharmaH. Hypothyroidism-induced reversible dilated cardiomyopathy.J. Postgrad. Med.201864317717910.4103/jpgm.JPGM_154_1729992912
     [Google Scholar]
  20. NakovaV.V. KrstevskaB. KostovskaE.S. VaskovaO. IsmailL.G. The effect of levothyroxine treatment on left ventricular function in subclinical hypothyroidism.Arch. Endocrinol. Metab.201862439239810.20945/2359‑399700000005230304103
     [Google Scholar]
  21. LadensonP.W. ShermanS.I. BaughmanK.L. RayP.E. FeldmanA.M. Reversible alterations in myocardial gene expression in a young man with dilated cardiomyopathy and hypothyroidism.Proc. Natl. Acad. Sci. USA199289125251525510.1073/pnas.89.12.52511376915
     [Google Scholar]
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A Case Report of Severe Hypothyroidism-induced Cardiomyopathy and Anemia: The Concealed Cause
NEW Emirates Medical J 5, e02506882363676 (2024); https://doi.org/10.2174/0102506882363676241219043835
/content/journals/nemj/10.2174/0102506882363676241219043835
/content/journals/nemj/10.2174/0102506882363676241219043835
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  • Article Type:     Case Report
Keyword(s): Anemia; Cardiomyopathies; Dilated cardiomyopathy; Heart failure; Hypothyroidism; Thyroid gland disorder

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