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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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DNA Methylation Biomarkers in Serum for Gastric Cancer Screening
- Source: Mini Reviews in Medicinal Chemistry, Volume 10, Issue 11, Oct 2010, p. 1034 - 1038
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- 01 Oct 2010
Abstract
Epigenetic alterations occur throughout the development and carcinogenesis of gastric cancer. Therefore, the detection of methylated DNA markers is predicted to be able to detect gastric cancer earlier, and improve the risk assessment, surveillance, relapse, and prognosis of patients with gastric cancer. Detection of free methylated DNA also represents a promising approach for developing serum-based detection methods for the non-invasive monitoring of gastric cancer progression.
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