Full text loading...
- ISSN: 1389-5575
- E-ISSN: 1875-5607
-
Gastrin: An Acid-Releasing, Proliferative and Immunomodulatory Peptide?
- Source: Mini Reviews in Medicinal Chemistry, Volume 10, Issue 1, Jan 2010, p. 8 - 19
-
- 01 Jan 2010
Abstract
Gastrin release is affected by gastric inflammatory conditions. Antral G cells respond to inflammatory mediators by increasing gastrin secretion. Accumulating experimental evidence suggests that gastrin exerts immunomodulatory and proinflammatory effects. Gastrin could be a contributing factor to these pathologies, which may constitute a new justification for pharmacological blockade of gastrin action.
© Bentham Science Publishers