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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Ligands of Diltiazem Binding Site: An Overview of Some Chemotypes
- Source: Mini Reviews in Medicinal Chemistry, Volume 9, Issue 12, Oct 2009, p. 1379 - 1388
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- 01 Oct 2009
Abstract
The diltiazem binding site of L-type calcium channels is the least characterized to date. In this paper, we present some of the available chemotypes that bind to the benzothiazepine binding site: natural compounds, compounds synthesized by varying the benzothiazepine scaffold, and compounds discovered by means of computational approaches.
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