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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Novel Amphiphilic Hyperbranched Poly (amine-ester) Copolymers Nanoparticles as Protein Drug Delivery
- Source: Mini Reviews in Medicinal Chemistry, Volume 9, Issue 11, Oct 2009, p. 1342 - 1356
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- 01 Oct 2009
Abstract
Novel amphiphilic protein-loaded hyperbranched poly (amine-ester) copolymers nanoparticles were fabricated by double emulsion (DE) and nanoprecipitation (NP) methods. Encapsulation efficiency (EE) of nanoparticles to Bovine serum albumin (BSA) could reach 97.8% at BSA (0.01g/ml), internal phase volume (0.5ml), copolymer weight (50mg), and PVA concentration (4%, w/v) condition.
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