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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Cellular Efflux of cAMP and cGMP - A Question about Selectivity
- Source: Mini Reviews in Medicinal Chemistry, Volume 9, Issue 8, Jul 2009, p. 1009 - 1013
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- 01 Jul 2009
Abstract
The present paper reviews and discusses selectivity of ABCC4 (MRP4), ABCC5 (MRP5) and ABCC11 (MRP8) as cellular efflux pumps for cAMP and cGMP. These transporters are potential drug targets for selective modulation of cyclic nucleotide action.
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