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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Pharmacological and Lifestyle Factors Modulating Serum Paraoxonase-1 Activity
- Source: Mini Reviews in Medicinal Chemistry, Volume 9, Issue 8, Jul 2009, p. 911 - 920
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- 01 Jul 2009
Abstract
Paraoxonase-1 is a lactonase and an esterase and it plays a protective role in toxicity as well as in diseases involving oxidative stress. Recently, insights into how it may be modulated by environmental factors have acquired clinical relevance. This article reviews the state-of-the-art evidence regarding PON1 modulation by pharmacological products as well as nutritional and lifestyle factors.
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