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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Suramin: Clinical Uses and Structure-Activity Relationships
- Source: Mini Reviews in Medicinal Chemistry, Volume 8, Issue 13, Nov 2008, p. 1384 - 1394
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- 01 Nov 2008
Abstract
Suramin is a polysulfonated polyaromatic symmetrical urea. It is currently used to treat African river blindness and African sleeping sickness. Suramin has also been extensively trialed recently to treat a number of other diseases, including many cancers. Here, we examine its modes of action and discuss its structure-activity relationships.
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