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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Design of Selective G-quadruplex Ligands as Potential Anticancer Agents
- Source: Mini Reviews in Medicinal Chemistry, Volume 8, Issue 11, Oct 2008, p. 1163 - 1178
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- 01 Oct 2008
Abstract
G-quadruplex structures are promising targets for design of cancer drugs with high selectivity and low toxicity. This review provides an update of the progress made over the last few years in the design of selective G-quadruplex ligands, and a comprehensive summary of the major design strategies and structural characteristics.
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