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2000
Volume 8, Issue 8
  • ISSN: 1389-5575
  • E-ISSN: 1875-5607

Abstract

Nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor is a candidate target for novel therapeutics for a range of conditions, including obesity. This article reviews recent advances in understanding of N/OFQ's involvement in the regulation of food intake and appraises current developments in the rational design of antagonists aimed at the NOP receptor.

© Bentham Science Publishers
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/content/journals/mrmc/10.2174/138955708784912139
2008-07-01
2025-09-11

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  • Article Type:     Research Article
Keyword(s): food intake; kappa-type 3 opioid receptor (KOR-3); nociceptin/orphanin FQ peptide (NOP) receptor; Nociceptin/orphanin FQ, N/OFQ; obesity; opioid receptor like-1 (ORL-1); opioid receptor-4 (OP4); rat opioid receptor-C (ROR-C)

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