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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Inhibitors of c-jun-N-Terminal Kinase (JNK)
- Source: Mini Reviews in Medicinal Chemistry, Volume 8, Issue 8, Jul 2008, p. 755 - 766
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- 01 Jul 2008
Abstract
Inhibitors of c-jun-N-Terminal Kinase (JNK) have many potential therapeutic indications ranging from neurodegenerative disease, to metabolic disorders, inflammation, cardiovascular disease, and cancer. This overview will highlight biological inhibitors such as JNK-interacting protein (JIP) as well as small molecule inhibitors from various structural classes including, aminopyrimidines and indazoles.
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