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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimer's Disease
- Source: Mini Reviews in Medicinal Chemistry, Volume 8, Issue 5, May 2008, p. 429 - 435
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- 01 May 2008
Abstract
Beta-amyloid (Aβ) likely plays a pivotal role in the etiology of Alzheimer's disease (AD). Consequently, Aβ-associated pathways are targets for the development of possible effective AD therapies. This review first updates strategies aimed at the inhibition of Aβ formation and then discusses the role of food-derived polyphenols as putative antiamyloid drugs.
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