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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Carbonyl-Scavenging Drugs & Protection Against Carbonyl Stress-Associated Cell Injury
- Source: Mini Reviews in Medicinal Chemistry, Volume 8, Issue 4, Apr 2008, p. 319 - 330
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- 01 Apr 2008
Abstract
This mini-review highlights the chemical and cytoprotective properties of various hydralazine analogues that block the induction of cell death by acrolein, a highly toxic contributor to “carbonyl stress” during a diverse range of human diseases. Recent work on the action of hydralazine against various carbonyl-mediated pathologies is also reviewed.
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