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2000
Volume 5, Issue 11
  • ISSN: 1389-5575
  • E-ISSN: 1875-5607

Abstract

Vanadate can be bioequivalent to phosphate and replace it in cellular metabolism. The detection of insulin-like activity has spurred interest in the development of oral anti-diabetic drugs containing vanadium. We collected and evaluated a vast toxicity data set and discussed molecular aspects related to insulin-mimetic effects of vanadium complexes.

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/content/journals/mrmc/10.2174/138955705774575264
2005-11-01
2025-09-01

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  • Article Type:     Review Article
Keyword(s): anti-diabetic; insulin-mimetic; molecular design; phospho-mimetic; ptp-1b; toxicity; vanadium

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