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2000
Volume 5, Issue 2
  • ISSN: 1389-5575
  • E-ISSN: 1875-5607

Abstract

The key importance of lipophilicity in bio-studies is discussed for ß-blockers. Examples of their lipophilicity-dependent pharmacological properties including pharmacokinetic, pharmacodynamic and clinical aspects are reviewed. Comprehensive lipophilicity compilations of ß-blockers are lacking so far. LogP calculations with 10 programs for 30 clinically relevant ß-blockers are presented for the first time in this review.

© Bentham Science Publishers
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/content/journals/mrmc/10.2174/1389557053402701
2005-02-01
2025-09-03

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  • Article Type:     Review Article
Keyword(s): blockers; lipophilicity; logp calculation programs; logp compilation for β-blockers; pharmacodynamic and clinical properties; pharmacokinetic

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