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2000
Volume 4, Issue 6
  • ISSN: 1389-5575
  • E-ISSN: 1875-5607

Abstract

The estimation and use of synthetic accessibility in the drug discovery process is discussed. A distinction is drawn between synthetic feasibility and accessibility and the practical uses of an accessibility score are examined. Various techniques used in the estimation of accessibility are described and their utility and potential accuracy compared.

© Bentham Science Publishers
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/content/journals/mrmc/10.2174/1389557043403765
2004-08-01
2025-09-11

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  • Article Type:     Review Article
Keyword(s): drug development; drug discovery; prioritization; retrosynthetic analysis; screening; synthetic accessibility; synthetic feasibility

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