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2000
Volume 4, Issue 7
  • ISSN: 1389-5575
  • E-ISSN: 1875-5607

Abstract

Recent advances in structure determination and computational methods have encouraged the development of structure-based virtual screening. Here we survey progress in the field and review the most recent methods, validation experiments and real applications, including an in-house example of hit identification for the oncology target Hsp90. These results provide a basis for discussing the current state of structure-based virtual screening and to outline the developments that are expected to have a major impact in the near future.

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/content/journals/mrmc/10.2174/1389557043403675
2004-09-01
2025-10-21
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/content/journals/mrmc/10.2174/1389557043403675
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