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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Towards Alzheimer's Disease Vaccination
- Source: Mini Reviews in Medicinal Chemistry, Volume 2, Issue 1, Feb 2002, p. 85 - 92
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- 01 Feb 2002
Abstract
Active and passive immunization against fibrillar β-amyloid of various mice models of Alzheimer's disease leads to the disaggregation and inhibition of plaque formation. Preliminary results showing improved behaviour and memory function obtained after administration of anti-β-amyloid vaccines to transgenic mice encourage these and related approaches for testing in the treatment and prevention of Alzheimer's disease.
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