Full text loading...
- ISSN: 1389-5575
- E-ISSN: 1875-5607
-
Non Peptidic Ligands at the Opioid Receptor Like-1 (ORL-1)
- Source: Mini Reviews in Medicinal Chemistry, Volume 1, Issue 4, Nov 2001, p. 363 - 375
-
- 01 Nov 2001
Abstract
Opioid receptor like-1 (ORL-1) has recently been indicated as a potentially useful target for the treatment of a number of central disorders and several other diseases.This review deals with non-peptidic ligands at the ORL-1 receptor, focusing on their structural and binding properties. Agonism or antagonism evidenced from functional experiments is also commented. For some compounds, possible therapeutic applications are considered.
© Bentham Science Publishers