Novel Therapeutic Targets for Acute Pancreatitis and Associated Multiple Organ Dysfunction Syndrome: An Update

In an article published in Current Drug Targets - Inflammation and Allergy in December 2002, I had reviewed the critical role played by inflammatory mediators in the pathogenesis of acute pancreatitis and associated multiple organ dysfunction syndrome (MODS) and the potential for these mediators as therapeutic targets. Recent work, by us as well as other investigators, has further substantiated a potential for these mediators as therapeutic targets for this condition.