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2000
Volume 25, Issue 13
  • ISSN: 1871-5303
  • E-ISSN: 2212-3873

Abstract

Reactive oxygen species production, inflammation, an elevated serum profile, mitochondrial dysfunction, and up-regulation of proapoptotic mediators are the main mechanisms underlying chemotherapy-related hepatotoxicity, which results in hepatocyte disorders such as hepatitis, steatohepatitis, and fibrosis. The article aims to examine a prospective herbal remedy and its bioactive ingredients in terms of its antioxidant, anti-inflammatory, and anti-apoptotic capabilities, which offer superior protection against liver damage during chemotherapy administration. Plants including , , , , and may have hepatoprotective properties, according to the author. Last but not least, this will give aspiring scientists new knowledge for natural-based development in mitigating liver damage caused by chemotherapy medications.

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2025-12-15

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Ameliorative Effect of Herbal Medicine in the Management of Hepatotoxicity
Endocr Metab Immune Disord Drug Targets 25, 1035 (2025); https://doi.org/10.2174/0118715303319815240819053924
/content/journals/emiddt/10.2174/0118715303319815240819053924
/content/journals/emiddt/10.2174/0118715303319815240819053924
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  • Article Type:     Review Article
Keyword(s): anti-inflammatory; antioxidant; Chemotherapy; flavonoid; hepatoprotective; herbal medicine

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