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- ISSN: 1872-2148
- E-ISSN: 2212-3334
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MAVS: A New Weapon in the Fight Against Viral Infections
- Source: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery, Volume 7, Issue 2, May 2013, p. 115 - 119
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- 01 May 2013
Abstract
In addition to their participation in metabolic processes and control of programmed cell death, the role of mitochondria as a fundamental hub for innate anti-viral immunity is now emerging. The participation of the mitochondrial antiviral signaling protein (MAVS) as a central regulator of a complex signaling cascade, which results in the induction of antiviral and inflammatory responses has been described. A patent based on this role of MAVS is highlighted in this review.
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