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- ISSN: 1872-3128
- E-ISSN: 1874-0758
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Covariates of Amikacin Clearance in Neonates: The Impact of Postnatal Age on Predictability
- Source: Drug Metabolism Letters, Volume 2, Issue 4, Dec 2008, p. 286 - 289
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- 01 Dec 2008
Abstract
An earlier reported population pharmacokinetic study documented limited predictability of amikacin clearance (65%) at birth. An exercise in the first month of life resulted in extended predictability (92%) with similar clearance estimates after the first postnatal days, reflecting the impact of postnatal age on clearance predictability.
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