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- ISSN: 1872-3128
- E-ISSN: 1874-0758
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Antioxidants Suppress Th1-Type Immune Response In Vitro
- Source: Drug Metabolism Letters, Volume 1, Issue 3, Aug 2007, p. 166 - 171
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- 01 Aug 2007
Abstract
Inflammation is a hallmark of various diseases like infections, autoimmune syndromes, cardiovascular and neurodegenerative disorders, and cancer. Thereby, Th1-type cytokine interferon-γ is a central pro-inflammatory mediator. Antioxidant compounds counteract the activation of T-cells and macrophages. This anti-inflammatory activity could be important for the development of immunotolerance and for treatment of above-mentioned disorders.
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