A Pilot Study Evaluating Therapeutic Efficacy of Siddha Formulation ‘Nandukkal Parpam’ in the Management of Renal Calculi

Objective: The present pilot study was designed to evaluate the effect of Nandukkal parpam (Calx of Fossil stone crab) a Traditional Siddha medicine in Kalladaippu (Urolithiasis) patients. Method: This study was conducted at the National Institute of Siddha, Tambaram, Chennai, India. The investigator recruited 10 patients with an inclusion and exclusion criteria. The patients were treated with 260 mg of Nandukkal parpam along with 50 ml Sirupeelai kudineer (freshly prepared decoction of the whole plant of Aerva lanata – Mountain Knot grass) twice a day for a period of 60 days. All the patients were taken laboratory investigations and Ultra Sono Gram (USG-KUB). Results: Normal sonographic study was observed in 6 patients and reduction in number of stones and stone size in 4 patients. There were no adverse events reported during the study and no recurrences during the follow up period of up to one year were reported. Conclusion: Results suggest that the trial drug Nandukkal parpam is effective and safe for the management of Kalladaippu (Urolithiasis) and in alleviating recurrences.