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2000
Volume 11, Issue 4
  • ISSN: 2215-0838
  • E-ISSN: 2215-0846

Abstract

Background and Objective

Episiotomy, worldwide, is the most frequently performed obstetric surgical procedure. Delayed wound healing potentially amplifies the risk of wound infection, structural muscular alterations, and ultimately contributes to the loss of muscle tone. In addition, rapid and complete repair of the episiotomy or perineal tear is very important as the pain and discomfort of episiotomy wounds may affect the quality of life of postnatal mothers. Therefore, we aimed to determine the efficacy of ointment and alum perineal wash on perineal wound healing and pain intensity in postnatal mothers.

Materials and Methods

A single-arm self-controlled study was conducted on postnatal mothers aged 18 to 40 years, who underwent full-term normal cephalic singleton vaginal delivery with episiotomy and/or 1st, 2nd, or 3rd-degree perineal tears. The recommended external care regimen for a period of 10 days involved perineal wash with a solution of alum powder (2 gm/500 ml), followed by the application of ointment twice daily to the perineal wound. For the primary evaluation of wound healing, the REEDA (redness, edema, ecchymosis, discharge, and approximation) scale has been utilized, while the secondary assessment involved the use of the VAS (visual analog scale) pain intensity scale. The therapeutic outcome was determined based on the grading of REEDA scores on days 10-14 and VAS scores.

Results

We observed our trial medicine showed complete wound healing in 86.4% on days 10-14. The mean pain reduction percentage (PR %) was 96.85% on days 10-14 from baseline. The REEDA score was 2.41 ± 0.81 and 0.23 ± 0.61 at one hour and day 10-14, respectively, with significant differences ( < 0.001). The VAS score was 2.86 ± 1.08 and 0.09 ± 0.29 at one hour and day 10-14, respectively, with significant differences ( < 0.001). Therefore, the trial ointment and alum have demonstrated beneficial effects in promoting perineal wound healing and alleviating pain in postnatal mothers.

Conclusion

The potential efficacy of can be attributed to its composition of various phytoconstituents, such as oleuropein, phenolic acids, flavonols, flavones, linoleic acid isovitexin, vitexin vanillic acid, salicylic acid, beta-D-glucopyranoside, olanigroside Y1, solasonine, gallic acid, aucubin, scopoletin, and lantamajoside. These constituents have been proven in research studies to possess anti-inflammatory, wound healing, antimicrobial, analgesic, and antioxidant properties. The investigators have optimized the use of these Unani medicines to provide clinical evidence supporting their effectiveness in the wound-healing process and in reducing pain intensity.

Clinical Trial Registration Number

CTRI/2021/09/036714.

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2025-11-06

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Efficacy of Marham-e-Dakhilyun Ointment and Alum Perineal Wash for Perineal Wound Healing and Pain Intensity in Postpartum Women: A Self-control Clinical Trial
Current Traditional Medicine 11, e270224227465 (2025); https://doi.org/10.2174/0122150838268744231221100158
/content/journals/ctm/10.2174/0122150838268744231221100158
/content/journals/ctm/10.2174/0122150838268744231221100158
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  • Article Type:     Research Article
Keyword(s): drug design; Episiotomy; herbal medicine; Marham-e-Dakhilyun; ointment; perineal wound healing; REEDA score; VAS pain intensity scale

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