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image of Discoid Lupus Flare with Chondritis Triggered by Eaton Fire Case Report

Abstract

Introduction

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder with flare-ups often triggered by environmental stressors. While stress is a known trigger for lupus exacerbations, the relationship between environmental stressors, lupus flares, and discoid lupus erythematosus remains underexplored. This case report examines a patient whose symptoms worsened after exposure to the Eaton fire.

Case Presentation

A 57-year-old female with lupus reported a flare following the Eaton fire, which severely damaged her parents' home. Symptoms began 12 hours after the fire. Examination revealed erythema and deformity in both ears, consistent with chondritis. After starting a prednisone taper, her condition improved within two weeks.

Conclusion

Environmental stressors, like natural disasters, can trigger lupus flare-ups and conditions, such as discoid lupus erythematosus (DLE). Stress-induced immune dysregulation exacerbates autoimmune responses, making it challenging to differentiate discoid lupus from other lupus manifestations. This case highlights the need for recognizing environmental triggers in lupus management and further research into the role of stress in lupus flare-ups.

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/content/journals/crr/10.2174/0115733971396962250721111020
2025-07-24
2025-11-01
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