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2000
Volume 21, Issue 4
  • ISSN: 1573-398X
  • E-ISSN: 1875-6387

Abstract

Obstructive Sleep Apnea (OSA) is identified by repetitive airway obstruction while sleeping, which affects decreased oxygen levels and fragmented sleeping. Structural contributors include a small jaw, enlarged adenoids, Down syndrome, and a low hyoid bone. Non-structural risk factors are obesity, older age, male sex, alcohol use, smoking, and neurological disorders. OSA is diagnosed based on obstructive respiratory events during sleep. Chronic Obstructive Pulmonary Disease (COPD) encompasses the chronic emphysema and bronchitis. Both are marked by persistent symptoms that significantly impact respiratory function. Chronic bronchitis can be identified by a long-term cough along with the production of mucus, while emphysema involves the gradual destruction of the air sacs in the lungs, leading to difficulty in breathing. Together, these conditions result in ongoing shortness of breath, reduced airflow, and a decreased ability to perform everyday activities, severely affecting life for those affected patients. “Overlap syndrome” refers to the coexistence of COPD and OSA. In these patients, sleep worsens breathing difficulties, leading to significant oxygen desaturation, especially during REM sleep. This results from airway obstructions and reduced respiratory drive, with factors like smoking and corticosteroid use exacerbating the condition.

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Risk of Obstructive Sleep Apnea in COPD Patients
Curr. Respir. Med. Rev. 21, 355 (2025); https://doi.org/10.2174/011573398X354337250214104212
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  • Article Type:     Review Article
Keyword(s): Airway obstruction; chronic obstructive pulmonary disease (COPD); obstructive sleep apnea (OSA); overlap syndrome, down syndrome, neurological disorders

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