Skip to content
2000
Volume 21, Issue 4
  • ISSN: 1573-3963
  • E-ISSN: 1875-6336

Abstract

Background

In dental extractions, particularly when local anesthesia is used, it usually offers analgesic relief for a few hours. However, pain can become a notable concern in the immediate postoperative period due to the trauma experienced by both soft and hard oral tissues.

Objectives

This systematic review aimed to evaluate the most effective strategies for managing postoperative pain in primary tooth extractions.

 Methods

Two examiners conducted a search across electronic databases: MEDLINE ( PubMed), Embase, Scopus, Web of Science, CENTRAL, and OpenGray. Studies were included if they met the following criteria after reviewing their titles and abstracts: they involved children and evaluated pain management following primary tooth extraction. Subsequently, articles that described extractions performed under any form of sedation, were not conducted under local anesthesia, in an outpatient setting, and in children aged 0 to 12 years, or were not randomized controlled trials, were excluded.

Results

The search yielded 374 relevant articles, of which 9 were included. Among these, 5 utilized preoperative medications as a pain management strategy, one evaluated low-level laser therapy (LLLT) postoperatively, one assessed calendula drops postoperatively, and another explored virtual reality during the procedure and arnica in solution both pre and postoperatively.

Conclusion

Among all the strategies evaluated, the strategy involving analgesics administered 30 minutes before tooth extractions was supported by better-designed studies. However, there is a high risk of bias.

Loading

Article metrics loading...

/content/journals/cpr/10.2174/0115733963292710240725051920
2024-08-13
2025-09-08
Loading full text...

Full text loading...

References

  1. RajaS. CarrD. CohenM. FinnerupN. FlorH. GibsonS. The Revised IASP definition of pain: concepts, challenges, and compromises. Pain [revista en Internet] 2021 [acceso 4 de marzo de 2022]; 161(9): 1-16.Pain202116191976198210.1097/j.pain.000000000000193932694387
    [Google Scholar]
  2. SjögrenA. ArnrupK. JensenC. KnutssonI. HuggareJ. Pain and fear in connection to orthodontic extractions of deciduous canines.Int. J. Paediatr. Dent.201020319320010.1111/j.1365‑263X.2010.01040.x20409200
    [Google Scholar]
  3. O’DonnellA. HendersonM. FearneJ. O’DonnellD. Management of postoperative pain in children following extractions of primary teeth under general anaesthesia: a comparison of paracetamol, Voltarol and no analgesia.Int. J. Paediatr. Dent.200717211011510.1111/j.1365‑263X.2006.00800.x17263861
    [Google Scholar]
  4. RaslanN. ZouzouT. Comparison of preemptive ibuprofen, acetaminophen, and placebo administration in reducing peri- and postoperative pain in primary tooth extraction: A randomized clinical trial.Clin. Exp. Dent. Res.2021761045105210.1002/cre2.46534121357
    [Google Scholar]
  5. SantosP.S. MassignanC. de OliveiraE.V. Miranda SantanaC. BolanM. CardosoM. Does the pre-emptive administration of paracetamol or ibuprofen reduce trans- and post-operative pain in primary molar extraction? A randomized placebo-controlled clinical trial.Int. J. Paediatr. Dent.202030678279010.1111/ipd.1264932268439
    [Google Scholar]
  6. ParriniS. ChisciG. LeonciniS. SignoriniC. VolpiN. CapuanoA. CiccoliL. De FeliceC. F2-Isoprostanes in soft oral tissues and degree of oral disability after mandibular third molar surgery.Oral Surg. Oral Med. Oral Pathol. Oral Radiol.2012114334434910.1016/j.oooo.2012.03.01022862975
    [Google Scholar]
  7. ChoH. LynhamA. J. HsuE. Postoperative interventions to reduce inflammatory complications after third molar surgery: review of the current evidence.Australian Dental Journal201762441241910.1111/adj.12526
    [Google Scholar]
  8. ChisciG. ChisciC. ChisciV. ChisciE. Ocular complications after posterior superior alveolar nerve block: a case of trochlear nerve palsy.Int. J. Oral Maxillofac. Surg.201342121562156510.1016/j.ijom.2013.05.01023809987
    [Google Scholar]
  9. ØyriH. JonsdottirO. JensenJ.L. BjørnlandT. The use of a tetracycline drain reduces alveolar osteitis: a randomized prospective trial of third molar surgery under local anesthetics and without the use of systemic antibiotics.Oral Surg. Oral Med. Oral Pathol. Oral Radiol.2019128320521210.1016/j.oooo.2018.12.00431221615
    [Google Scholar]
  10. GhafoorH. HaroonS. AtiqueS. Ul HudaA. AhmedO. Bel KhairA.O.M. Abdus SamadA. Neurological Complications of Local Anesthesia in Dentistry: A Review.Cureus20231512e5079010.7759/cureus.5079038239523
    [Google Scholar]
  11. SteenenS.A. DuboisL. SaeedP. De LangeJ. Ophthalmologic complications after intraoral local anesthesia: Case report and review of literatureOral Surgery, Oral Medicine Oral Pathology and Oral Radiology2012113610.1016/j.tripleo.2011.07.032
    [Google Scholar]
  12. JahanimoghadamJ. HodaS. ShokrizadehM. Postoperative or preoperative medication? Which one is more effective in the management of postoperative extraction dental pain in children?J. Oral Health Oral Epidemiol.2021101435010.22122/johoe.v10i1.1100
    [Google Scholar]
  13. ElbayÜ.Ş. TakÖ. ElbayM. UğurluelC. KayaC. Efficacy of Low-Level Laser Therapy in the Management of Postoperative Pain in Children After Primary Teeth Extraction: A Randomized Clinical Trial.Photomed. Laser Surg.201634417117710.1089/pho.2015.404526977740
    [Google Scholar]
  14. KaurB. DixitU. Khaur et al.2016Jk-Practioner2016211-2
    [Google Scholar]
  15. PageMJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.BMJ.2021372n7110.1136/bmj.n71
    [Google Scholar]
  16. SchardtC. AdamsM.B. OwensT. KeitzS. FonteloP. Utilization of the PICO framework to improve searching PubMed for clinical questions.BMC Med. Inform. Decis. Mak.2007711610.1186/1472‑6947‑7‑1617573961
    [Google Scholar]
  17. BayginO. TuzunerT. IsikB. KusgozA. TanriverM. Comparison of pre-emptive ibuprofen, paracetamol, and placebo administration in reducing post-operative pain in primary tooth extraction.Int. J. Paediatr. Dent.201121430631310.1111/j.1365‑263X.2011.01124.x21470320
    [Google Scholar]
  18. PrimoschF.R.E. NicholsM.L. CourtsJ. Comparison of preoperative ibuprofen, acetaminophen, and placebo administration on the parental report of postextraction pain in children.1995187191
    [Google Scholar]
  19. PathakP.D. LakadeL.S. PatilK.V. ShahP.P. PatelA.R. DavalbhaktaR.N. Clinical evaluation of feasibility and effectiveness using a virtual reality device during local anesthesia and extractions in pediatric patients.Eur. Arch. Paediatr. Dent.202324337938610.1007/s40368‑023‑00801‑637184588
    [Google Scholar]
  20. KatreA.N. ThakurJ.H. Comparison of the Efficacy of Homeopathic Drug Arnica and Ibuprofen on Postextraction Pain in Children: A Triple-blind Randomized Controlled Trial.Int. J. Clin. Pediatr. Dent.202215333233710.5005/jp‑journals‑10005‑237935991790
    [Google Scholar]
  21. PfA. ParekhS. AnandP. LciM. Preoperative analgesics for additional pain relief in children and adolescents having dental treatment (Review).201610.1002/14651858.CD008392.pub3.www.cochranelibrary.com
    [Google Scholar]
  22. JacksonD.L. MooreP.A. HargreavesK.M. Preoperative nonsteroidal anti-inflammatory medication for the prevention of postoperative dental pain.J. Am. Dent. Assoc.1989119564164710.1016/S0002‑8177(89)95018‑62691542
    [Google Scholar]
  23. HallL. Suppression of Postoperative Painby Preoperative Administration of Ibuprofen in Comparison to Placebo, Acetaminophen, andAcetaminophen PlusCodeine19833743
    [Google Scholar]
  24. BaileyE. WorthingtonH. CoulthardP. Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth, a Cochrane systematic review.Br. Dent. J.2014216845145510.1038/sj.bdj.2014.33024762895
    [Google Scholar]
  25. Amorim JúniorL.A. RodriguesV.B.M. CostaL.R. Corrêa-FariaP. Is dental anxiety associated with the behavior of sedated children?Braz. Oral Res.202135e08810.1590/1807‑3107bor‑2021.vol35.008834378670
    [Google Scholar]
  26. Ramos-JorgeJ. MarquesL.S. HomemM.A. PaivaS.M. FerreiraM.C. Oliveira FerreiraF. Ramos-JorgeM.L. Degree of dental anxiety in children with and without toothache: prospective assessment.Int. J. Paediatr. Dent.201323212513010.1111/j.1365‑263X.2012.01234.x22436029
    [Google Scholar]
  27. FariaP.V. Raquel Lourdes; Cardoso, Lincoln Marcelo Lourenço; Akisue, Gokithi; Pereira, Cristiane Aparecida; Junqueira, Juliana Campos; Jorge, Antonio Olavo Cardoso; Santos Júnior, “Adherence of microorganisms to sutures after extraction of unerupted third molars” in vivo 2011195476482
  28. AlexandreJ.T.M. SousaL.H.T. LisboaM.R.P. FurlanetoF.A.C. do ValD.R. MarquesM. VasconcelosH.C. de MeloI.M. LeitãoR. Castro BritoG.A. GoesP. Anti-inflammatory and antiresorptive effects of Calendula officinalis on inflammatory bone loss in rats.Clin. Oral Investig.20182262175218510.1007/s00784‑017‑2308‑729288400
    [Google Scholar]
  29. IannittiT. Morales-MedinaJ.C. BellaviteP. RottigniV. PalmieriB. Effectiveness and Safety of Arnica montana in Post-Surgical Setting, Pain and Inflammation.Am. J. Ther.2016231e184e19710.1097/MJT.000000000000003625171757
    [Google Scholar]
  30. Santos-PintoL. PaschoalM. SouzaJ. PansaniC. Alternative approach to the management of postoperative pain after pediatric surgical procedures.Int. J. Clin. Pediatr. Dent.20147212512910.5005/jp‑journals‑10005‑124925356012
    [Google Scholar]
  31. ArmfieldJ.M. SpencerA.J. StewartJ.F. Armfield2006.Aust. Dent. J.2006511788510.1111/j.1834‑7819.2006.tb00405.x16669482
    [Google Scholar]
  32. AtzoriB. Lauro GrottoR. GiugniA. CalabròM. AlhalabiW. HoffmanH.G. Virtual reality analgesia for pediatric dental patients.Front. Psychol.20189NOV226510.3389/fpsyg.2018.0226530532720
    [Google Scholar]
/content/journals/cpr/10.2174/0115733963292710240725051920
Loading
/content/journals/cpr/10.2174/0115733963292710240725051920
Loading

Data & Media loading...

Supplements

PRISMA checklist is available as supplementary material on the publisher’s website along with the published article.

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test