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2000
Volume 21, Issue 4
  • ISSN: 1573-3963
  • E-ISSN: 1875-6336

Abstract

Background

Asthma is a chronic atopic and inflammatory bronchial disease characterized by recurring symptoms, episodic reversible bronchial obstruction and easily triggered bronchospasms. Asthma often begins in childhood. International guidelines are widely accepted and implemented; however, there are similarities and differences in the management approaches. There is no national guideline in many cities in Asia. This review aims to provide a practical perspective on current recommendations in the management of childhood asthma, specifically in the following aspects: diagnosis, classification of severity, treatment options, and asthma control, and to provide physicians with up-to-date information for the management of asthma.

Methods

We used the PubMed function of Clinical Queries and searched keywords of “Asthma”, “Pediatric” AND “Guidelines” as the search engine. “Clinical Prediction Guides”, “Etiology”, “Diagnosis”, “Therapy,” “Prognosis,” and “Narrow” scope were used as filters. The search was conducted in November 2022. The information retrieved from this search was used in compiling the present article.

Results

Diagnosis is clinically based on symptom pattern, response to therapy with bronchodilators and inhaled corticosteroids, and spirometric pulmonary function testing (PFT). Asthma is classified in accordance with symptom frequency, peak expiratory flow rate (PEFR), forced expiratory volume in one second (FEV1), and atopic nonatopic etiology, where atopy means a predisposition toward a type 1 hypersensitivity reaction. Asthma is also classified as intermittent or persistent (mild to severe). Unfortunately, there is no disease cure for asthma. However, symptoms can be prevented by trigger avoidance and suppressed with inhaled corticosteroids. Antileukotriene agents or long-acting beta-agonists (LABA) may be used together with inhaled corticosteroids if symptoms of asthma are not controlled. Rapidly worsening symptoms are usually treated with an inhaled short-acting beta-2 agonist (SABA, , salbutamol) and oral corticosteroids. Intravenous corticosteroids and hospitalization are required in severe cases of asthma attacks. Some guidelines also provide recommendations on the use of biologics and immunotherapy.

Conclusion

Asthma is diagnosed clinically, with supporting laboratory testing. Treatment is based on severity classification, from intermittent to persistent. Inhaled bronchodilator and anti-inflammatory corticosteroid form the main stay of management.

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References

  1. PorsbjergC. MelénE. LehtimäkiL. ShawD. AsthmaLancet London, England202310.1016/S0140‑6736(22)02125‑0
     [Google Scholar]
  2. HonK.L. WangS.S. LeungT.F. HonKLE The atopic march: from skin to the airways.Iran. J. Allergy Asthma Immunol.2012111737722427479
     [Google Scholar]
  3. AgarwalR. DhooriaS. AggarwalA.N. MaturuV.N. SehgalI.S. MuthuV. PrasadK.T. YengeL.B. SinghN. BeheraD. JindalS.K. GuptaD. BalamugeshT. BhallaA. ChaudhryD. ChhabraS.K. ChokhaniR. ChopraV. DadhwalD.S. D’SouzaG. GargM. GaurS.N. GopalB. GhoshalA.G. GuleriaR. GuptaK.B. HaldarI. JainS. JainN.K. JainV.K. JanmejaA.K. KantS. KashyapS. KhilnaniG.C. KishanJ. KumarR. KoulP.A. MahashurA. MandalA.K. MalhotraS. MohammedS. MohapatraP.R. PatelD. PrasadR. RayP. SamariaJ.K. SinghP.S. SawhneyH. ShafiqN. SharmaN. SidhuU.P. SinglaR. SuriJ.C. TalwarD. VarmaS. Guidelines for diagnosis and management of bronchial asthma: Joint ICS/NCCP (I) recommendations.Lung India201532Suppl. 1S3S4210.4103/0970‑2113.15451725948889
     [Google Scholar]
  4. LeeD.L. BaptistA.P. Understanding the updates in the asthma guidelines.Semin. Respir. Crit. Care Med.202243559561210.1055/s‑0042‑174574735728605
     [Google Scholar]
  5. GuptaR.S. WeissK.B. The 2007 national asthma education and prevention program asthma guidelines: Accelerating their implementation and facilitating their impact on children with asthma.Pediatrics2009123Suppl. 3S193S19810.1542/peds.2008‑2233J19221163
     [Google Scholar]
  6. KhanL. Overview of the updates for the management of asthma guidelines.Pediatr. Ann.2022514e132e13510.3928/19382359‑20220317‑0335417311
     [Google Scholar]
  7. MoroscoG. KileyJ. National Asthma Education and Prevention Program Expert panel report 3 (EPR-3): Guidelines for the diagnosis and management of asthma–summary report 2007.J. Allergy Clin. Immunol.20071205Suppl.S94S13810.1016/j.jaci.2007.09.02917983880
     [Google Scholar]
  8. UrbanoF.L. Review of the NAEPP 2007 expert panel report (EPR-3) on asthma diagnosis and treatment guidelines.J. Manag. Care Pharm.2008141414910.18553/jmcp.2008.14.1.4118240881
     [Google Scholar]
  9. National asthma education and prevention program. Expert panel report 3 (EPR-3): Guidelines for the diagnosis and management of asthma-summary report 2007J Allergy Clin Immunol.20071205 SupplS94S138
     [Google Scholar]
  10. Global strategy for asthma management and prevention updated 20112011
     [Google Scholar]
  11. Asthma-Level 3 cause.Lancet2020396S108S109
     [Google Scholar]
  12. AnandanC. NurmatovU. Van SchayckO.C.P. SheikhA. Is the prevalence of asthma declining? Systematic review of epidemiological studies.Allergy201065215216710.1111/j.1398‑9995.2009.02244.x19912154
     [Google Scholar]
  13. LemanskeR.F.Jr BusseW.W. Asthma: Clinical expression and molecular mechanisms.J. Allergy Clin. Immunol.20101252Suppl. 2S95S10210.1016/j.jaci.2009.10.04720176271
     [Google Scholar]
  14. YawnB.P. Factors accounting for asthma variability: Achieving optimal symptom control for individual patients.Prim. Care Respir. J.200817313814710.3132/pcrj.2008.0000418264646
     [Google Scholar]
  15. Guidelines for the Diagnosis and Management of Asthma 2007 (EPR-3) | NHLBI2007Available from: https://www.nhlbi.nih.gov/health-topics/guidelines-for-diagnosis-management-of-asthma
    [Google Scholar]
  16. LaiC.K.W. KoF.W.S. BhomeA. De GuiaT.S. WongG.W.K. ZainudinB.M.Z. NangN. BoonsawatW. ChoS.H. GunasekeraK.D. HongJ.G. HsuJ.Y. VietN.N. YunusF. MukhopadhyayA. Relationship between asthma control status, the asthma control test™ and urgent health-care utilization in asia.Respirology201116468869710.1111/j.1440‑1843.2011.01954.x21362102
     [Google Scholar]
  17. BouletL.P. FitzGeraldJ.M. ReddelH.K. The revised 2014 GINA strategy report.Curr. Opin. Pulm. Med.20152111710.1097/MCP.000000000000012525405667
     [Google Scholar]
  18. ScottJ.P. Peters-GoldenM. Antileukotriene agents for the treatment of lung disease.Am. J. Respir. Crit. Care Med.2013188553854410.1164/rccm.201301‑0023PP23822826
     [Google Scholar]
  19. HonKL. LeungTF. LeungAKC. Clinical effectiveness and safety of montelukast in asthma. What are the conclusions from clinical trials and meta-analyses? .Drug Des DevelTher2014883985010.2147/DDDT.S39100
     [Google Scholar]
  20. JonesC.C.S. BeckerE.A. CatramboneC.D. MartinM.A. A guideline-based approach to asthma management.Nurs. Clin. North Am.2013481354510.1016/j.cnur.2012.12.00723465445
     [Google Scholar]
  21. Guideline for the diagnosis and optimal management of asthma in childrenChinese J Pediatr.20165416718110.3760/CMA.J.ISSN.0578‑1310.2016.03.003
     [Google Scholar]
  22. ZhangB. JinR. GuanR.Z. LinR.J. ChangD.Y. ZhangL.H. DingJ. [Evaluation of the efficacy of chinese children’s asthma action plan on the long-term management of children with asthma at home].Z Honghua Y IX UE za Z Hi2020100463702370510.3760/CMA.J.CH112137‑20200408‑0112533342148
     [Google Scholar]
  23. ZhuK. XiangL. ShenK. Efficacy of Chinese children’s asthma action plan in the management of children with asthma.Allergy Asthma Proc.2020411e3e1010.2500/aap.2020.41.19001031888788
     [Google Scholar]
  24. HongJ. BaoY. ChenA. LiC. XiangL. LiuC. Chinese guidelines for childhood asthma 2016: Major updates, recommendations and key regional dataJ Asthma.2018551138114610.1080/02770903.2017.1396474
     [Google Scholar]
  25. ReddelH.K. BacharierL.B. BatemanE.D. BrightlingC.E. BrusselleG.G. BuhlR. CruzA.A. DuijtsL. DrazenJ.M. FitzGeraldJ.M. FlemingL.J. InoueH. KoF.W. KrishnanJ.A. LevyM.L. LinJ. MortimerK. PitrezP.M. SheikhA. YorganciogluA.A. BouletL.P. Global initiative for asthma strategy 2021: Executive summary and rationale for key changes.J. Allergy Clin. Immunol. Pract.2022101S1S1810.1016/j.jaip.2021.10.00134718211
     [Google Scholar]
  26. CloutierM.M. BaptistA.P. BlakeK.V. Brookse.g. Bryant-StephensT. DiMangoE. DixonA.E. ElwardK.S. HartertT. KrishnanJ.A. LemanskeR.F.Jr OuelletteD.R. PaceW.D. SchatzM. SkolnikN.S. StoutJ.W. TeachS.J. UmscheidC.A. WalshC.G. Focused updates to the asthma management guidelines: A report from the national asthma education and prevention program coordinating committee expert panel working group.J. Allergy Clin. Immunol.202014661217127010.1016/j.jaci.2020.10.00333280709
     [Google Scholar]
  27. HolguinF. CardetJ.C. ChungK.F. DiverS. FerreiraD.S. FitzpatrickA. GagaM. KellermeyerL. KhuranaS. KnightS. McDonaldV.M. MorganR.L. OrtegaV.E. RigauD. SubbaraoP. ToniaT. AdcockI.M. BleeckerE.R. BrightlingC. BouletL.P. CabanaM. CastroM. ChanezP. CustovicA. DjukanovicR. FreyU. FrankemölleB. GibsonP. HamerlijnckD. JarjourN. KonnoS. ShenH. VitaryC. BushA. Management of severe asthma: A European Respiratory Society/American Thoracic Society guideline.Eur. Respir. J.2020551190058810.1183/13993003.00588‑201931558662
     [Google Scholar]
  28. Asthma: Diagnosis, monitoring and chronic asthma management.LondonNational Institute for Health and Care Excellence (NICE)2021
     [Google Scholar]
  29. British guideline on the management of asthma A national clinical guideline www.sign.ac.uk/assets/sign50eqia.pdf.
     [Google Scholar]
  30. AgacheI. AkdisC.A. AkdisM. CanonicaG.W. CasaleT. ChivatoT. CorrenJ. ChuD.K. Del GiaccoS. EiweggerT. FloodB. FirinuD. GernJ.E. HamelmannE. HananiaN. Hernández-MartínI. KnibbR. MäkeläM. NairP. O’MahonyL. PapadopoulosN.G. PapiA. ParkH.S. Pérez de LlanoL. PfaarO. QuirceS. SastreJ. ShamjiM. SchwarzeJ. PalomaresO. JutelM. EAACI biologicals guidelines-recommendations for severe asthma.Allergy2021761144410.1111/all.1442532484954
     [Google Scholar]
  31. Australian Asthma Handbook https://www.asthmahandbook.org.au/ (Accessed March 1, 2023).
     [Google Scholar]
  32. MammenJ.R. McGovernC.M. Summary of the 2020 focused updates to U.S. Asthma management guidelines: What has changed and what hasn’t?J. Am. Assoc. Nurse Pract.202234223824110.1097/JXX.000000000000061934469362
     [Google Scholar]
  33. CloutierM.M. TeachS.J. LemanskeR.F.Jr BlakeK.V. The 2020 focused updates to the NIH asthma management guidelines: Key points for pediatricians.Pediatrics20211476e202105028610.1542/peds.2021‑05028633941586
     [Google Scholar]
  34. Asthma Management Guidelines: Focused Updates for 2020 - PubMed n.d. 2020Available from: https://pubmed.ncbi.nlm.nih.gov/34783488/ (accessed February18, 2023).
     [Google Scholar]
  35. Editorial Board Chinese Journal of Pediatrics, Subspecialty Group of Respiratory Diseases, the Society of Pediatrics, Chinese Medical Association, Children′s Respiratory Professional Committee, the Society of Pediatrics of Chinese Medical Doctor Association. [Recommendations for diagnosis and management of bronchial asthma in children (2020)]. Zhonghua Er Ke Za Zhi = Chinese.J. Pediatr.20205870871710.3760/CMA.J.CN112140‑20200604‑00578
     [Google Scholar]
  36. TanL.D. AlismailA. AriueB. Asthma guidelines: Comparison of the national heart, lung, and blood institute expert panel report 4 with global initiative for asthma 2021.Curr. Opin. Pulm. Med.202228323424410.1097/MCP.000000000000086735190509
     [Google Scholar]
  37. PijnenburgM.W. BaraldiE. BrandP.L.P. CarlsenK.H. EberE. FrischerT. HedlinG. KulkarniN. LexC. MäkeläM.J. MantzouranisE. MoellerA. PavordI. PiacentiniG. PriceD. RottierB.L. SaglaniS. SlyP.D. SzeflerS.J. ToniaT. TurnerS. WoolerE. Lødrup CarlsenK.C. Monitoring asthma in children.Eur. Respir. J.201545490692510.1183/09031936.0008881425745042
     [Google Scholar]
  38. PassalacquaG. CanonicaG.W. BagnascoD. Benefit of SLIT and SCIT for allergic rhinitis and asthma.Curr. Allergy Asthma Rep.201616128810.1007/s11882‑016‑0666‑x27957697
     [Google Scholar]
  39. HonK.L. FungC. LeungA. LeungT. NgD. Complementary and alternative medicine for childhood asthma: An overview of evidence and patents.Recent Pat. Inflamm. Allergy Drug Discov.201591667910.2174/1872213X0966615030210522525731179
     [Google Scholar]
  40. GrazianiE. PetroianniA. TerzanoC. Brittle asthma.Eur. Rev. Med. Pharmacol. Sci.20048413513815636398
     [Google Scholar]
  41. GallucciM. CarbonaraP. PacilliA.M.G. di PalmoE. RicciG. NavaS. Use of symptoms scores, spirometry, and other pulmonary function testing for asthma monitoring.Front Pediatr.201975410.3389/fped.2019.0005430891435
     [Google Scholar]
  42. IpM.S.M. KarlbergE.M. KarlbergJ.P. LukK.D.K. LeongJ.C. IpMS Lung function reference values in Chinese children and adolescents in Hong Kong. I. Spirometric values and comparison with other populations.Am. J. Respir. Crit. Care Med.2000162242442910.1164/ajrccm.162.2.990505710934064
     [Google Scholar]
  43. StanojevicS. WadeA. StocksJ. HankinsonJ. CoatesA.L. PanH. RosenthalM. CoreyM. LebecqueP. ColeT.J. Reference ranges for spirometry across all ages: A new approach.Am. J. Respir. Crit. Care Med.2008177325326010.1164/rccm.200708‑1248OC18006882
     [Google Scholar]
  44. ComberiatiP. KatialR.K. CovarR.A. Bronchoprovocation testing in asthma.Immunol. Allergy Clin. North Am.201838454557110.1016/j.iac.2018.06.01030342579
     [Google Scholar]
  45. ReddyC. Bronchoprovocation testing.Clin. Rev. Allergy Immunol.200937316717210.1007/s12016‑009‑8126‑119288293
     [Google Scholar]
  46. KatialR.K. CovarR.A. Bronchoprovocation testing in asthma.Immunol. Allergy Clin. North Am.201232341343110.1016/j.iac.2012.06.00222877619
     [Google Scholar]
  47. FujimotoK. KomatsuY. FujimotoK. HanaokaM. KuboK. Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment in patients with overlap syndrome of COPD and asthma.Int. J. Chron. Obstruct. Pulmon. Dis.2012728328910.2147/COPD.S3065122589579
     [Google Scholar]
  48. SahaK. BandyopadhyayA. RoyP.P. ChakrabortyS. JashD. SahaD. Usefulness of induced sputum eosinophil count to assess severity and treatment outcome in asthma patients.Lung India201330211712310.4103/0970‑2113.11041923741092
     [Google Scholar]
  49. KumarR. PajanivelR. KoteeswaranG. MenonS. CharlesP. Correlation of total serum immunoglobulin E level, sputum, and peripheral eosinophil count in assessing the clinical severity in bronchial asthma.Lung India201734325626110.4103/lungindia.lungindia_73_1628474652
     [Google Scholar]
  50. KansalP. NandanD. AgarwalS. PathariaN. AryaN. Correlation of induced sputum eosinophil levels with clinical parameters in mild and moderate persistent asthma in children aged 7–18 years.J. Asthma201855438539010.1080/02770903.2017.133872528696802
     [Google Scholar]
  51. JungJ.W. KimS.H. KwonJ.W. KimT.W. KangH.R. ParkH.W. KimS.S. ChangY.S. ChoS.H. MinK.U. COREA (Cohort for Reality and Evolution of adult Asthma) Research Group Clinical characteristics and long-term outcomes related to sputum eosinophilia in Korean asthmatics.Asia Pac. Allergy201111162410.5415/apallergy.2011.1.1.1622053292
     [Google Scholar]
  52. BrunnB. HapfelmeierA. JörresR.A. SchultzK. SchneiderA. Development of a diagnostic score using FeNO and symptoms to predict asthma.Respir. Med.202321510729910.1016/j.rmed.2023.10729937257788
     [Google Scholar]
  53. SchneiderA. WagenpfeilG. JörresR.A. WagenpfeilS. Influence of the practice setting on diagnostic prediction rules using FENO measurement in combination with clinical signs and symptoms of asthma.BMJ Open2015511e00967610.1136/bmjopen‑2015‑00967626603255
     [Google Scholar]
  54. KhatriS.B. IaccarinoJ.M. BarochiaA. SoghierI. AkuthotaP. BradyA. CovarR.A. DebleyJ.S. DiamantZ. FitzpatrickA.M. KaminskyD.A. KenyonN.J. KhuranaS. LipworthB.J. McCarthyK. PetersM. QueL.G. RossK.R. Schneider-FutschikE.K. SorknessC.A. HallstrandT.S. KhatriS.B. HallstrandT.S. AkuthotaP. BarochiaA. BradyA. CovarR.A. DebleyJ.S. DiamantZ. FitzpatrickA.M. IaccarinoJ.M. KaminskyD.A. KenyonN.J. KhuranaS. LipworthB.J. McCarthyK. PetersM. QueL.G. RossK.R. Schneider-FutschikE.K. SoghierI. SorknessC.A. American Thoracic Society Assembly on Allergy, Immunology, and Inflammation Use of fractional exhaled nitric oxide to guide the treatment of asthma: An official american thoracic society clinical practice guideline.Am. J. Respir. Crit. Care Med.202120410e97e10910.1164/rccm.202109‑2093ST34779751
     [Google Scholar]
  55. MurphyR.C. ZhangP. TejwaniV. KhatriS.B. HallstrandT.S. RuminjoJ.K. ThomsonC.C. Summary for clinicians: Clinical practice guideline for the use of fractional exhaled nitric oxide to guide the treatment of asthma.Ann. Am. Thorac. Soc.202219101627163010.1513/AnnalsATS.202204‑289CME35507440
     [Google Scholar]
  56. KnuffmanJ.E. SorknessC.A. LemanskeR.F.Jr MaugerD.T. BoehmerS.J. MartinezF.D. BacharierL.B. StrunkR.C. SzeflerS.J. ZeigerR.S. TaussigL.M. Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute Phenotypic predictors of long-term response to inhaled corticosteroid and leukotriene modifier therapies in pediatric asthma.J. Allergy Clin. Immunol.2009123241141610.1016/j.jaci.2008.11.01619121860
     [Google Scholar]
  57. FisherJ.D. SakariaR.P. SiddiquiK.N. IveyK.J. BaliL. BurnetteK. Initial ED oxygen saturation ≤90% increases the risk of a complicated hospital course in pediatric asthmatics requiring admission.Am. J. Emerg. Med.20193791743174510.1016/j.ajem.2019.06.02031230924
     [Google Scholar]
  58. KeaheyL. BullochB. BeckerA.B. PollackC.V.Jr ClarkS. CamargoC.A.Jr Multicenter Asthma Research Collaboration (MARC) Investigators Initial oxygen saturation as a predictor of admission in children presenting to the emergency department with acute asthma.Ann. Emerg. Med.200240330030710.1067/mem.2002.12681312192354
     [Google Scholar]
  59. BeasleyR. ChienJ. DouglasJ. EastlakeL. FarahC. KingG. MooreR. PilcherJ. RichardsM. SmithS. WaltersH. Target oxygen saturation range: 92–96% versus 94–98%.Respirology201722120020210.1111/resp.1287927587269
     [Google Scholar]
  60. ChavasseR.J.P.G. SeddonP. BaraA. McKeanM.C. Short acting beta2-agonists for recurrent wheeze in children under two years of age.Cochrane Libr.200220101CD00287310.1002/14651858.CD00287312137663
     [Google Scholar]
  61. KirkbyS. RossettiA. HayesD.Jr AllenE. SheikhS. KoppB. PatelA. Benefits of pulmonary rehabilitation in pediatric asthma.Pediatr. Pulmonol.20185381014101710.1002/ppul.2404129736958
     [Google Scholar]
  62. TrevorJ.L. BhattS.P. WellsJ.M. Kirkpatrick SchumannC. HitchcockJ. DransfieldM.T. Benefits of completing pulmonary rehabilitation in patients with asthma.J. Asthma201552996997310.3109/02770903.2015.102541026287942
     [Google Scholar]
  63. SahinH. NazI. Comparing the effect of pulmonary rehabilitation in patients with uncontrolled and partially controlled asthma.J. Asthma2019561879410.1080/02770903.2018.144346829533692
     [Google Scholar]
  64. LingnerH. ErnstS. GroβhennigA. DjahangiriN. ScheubD. WittmannM. SchultzK. Asthma control and health-related quality of life one year after inpatient pulmonary rehabilitation: The ProKAR Study.J. Asthma201552661462110.3109/02770903.2014.99665025494552
     [Google Scholar]
  65. JiangJ. ZhangD. HuangY. WuZ. ZhangW. Exercise rehabilitation in pediatric asthma: A systematic review and network meta-analysis.Pediatr. Pulmonol.202257122915292710.1002/ppul.2613436103241
     [Google Scholar]
  66. JinG. JiangY. ShaoH. ZhuJ. The effect of pulmonary rehabilitation on childhood asthma: A systematic review and meta-analysis.Minerva Pediatr.202375460461310.23736/S2724‑5276.21.06656‑837466066
     [Google Scholar]
  67. SheikhA. AlvesB. DhamiS. Pneumococcal vaccine for asthma.Cochrane Libr.200220146CD00216510.1002/14651858.CD00216511869626
     [Google Scholar]
  68. BoikosC. QuachC. Risk of invasive pneumococcal disease in children and adults with asthma: A systematic review.Vaccine201331424820482610.1016/j.vaccine.2013.07.07923965221
     [Google Scholar]
  69. CatesC.J. RoweB.H. Vaccines for preventing influenza in people with asthma.Cochrane Libr.201320132CD00036410.1002/14651858.CD000364.pub423450529
     [Google Scholar]
  70. JoshiA.Y. IyerV.N. HartzM.F. PatelA.M. LiJ.T. Effectiveness of trivalent inactivated influenza vaccine in influenza-related hospitalization in children: A case-control study.Allergy Asthma Proc.2012332232710.2500/aap.2012.33.351322525386
     [Google Scholar]
  71. GrahamV. LassersonT.J. RoweB.H. Antibiotics for acute asthma.Cochrane Libr.20013CD00274110.1002/14651858.CD00274111687022
     [Google Scholar]
  72. TesseR. BorrelliG. MongelliG. MastrorilliV. CardinaleF. Treating pediatric asthma according guidelines.Front Pediatr.2018623410.3389/fped.2018.0023430191146
     [Google Scholar]
  73. NormansellR. SayerB. WatersonS. DennettE.J. Del FornoM. DunleavyA. Antibiotics for exacerbations of asthma.Cochrane Libr.201820186CD00274110.1002/14651858.CD002741.pub229938789
     [Google Scholar]
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Insights from Overviewing Selective International Guidelines for Pediatric Asthma
Curr Pediatr Rev 21, 315 (2025); https://doi.org/10.2174/0115733963270829231221062201
/content/journals/cpr/10.2174/0115733963270829231221062201
/content/journals/cpr/10.2174/0115733963270829231221062201
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  • Article Type:     Review Article
Keyword(s): Asthma; beta agonists; guidelines; inhaled corticosteroid, biologics; laboratory testing

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