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2000
Volume 4, Issue 1
  • ISSN: 2666-7797
  • E-ISSN: 2666-7800

Abstract

Background/Introduction

Bakuchiol is a meroterpene and is utilized in many cosmetic preparations in the form of as a substitute for retinoids. The calyx of flowers is rich in carotenoids. The standardized ethanolic extract of the calyx indicated the presence of a yellow-orange colour pigment, which was found identical to crocin, an apocarotenoid present in saffron. Hence, orange-coloured tubular calyx of can be utilized as a substitute for saffron.

Objective

To utilize the tubular calyx of as an economical source of crocin and seed as a source of bakuchiol for the development of a stable hydrogel formulation as well as evaluation of its antiaging activity and sunscreen property.

Methodology

Crocin-rich ethanolic extract calyx of was prepared using the maceration method. The seeds of were extracted using petroleum ether (60-80) using a Soxhlet extractor. Hydrogel formulation was prepared using crocin-rich extract and bakuchiol-rich extract. Evaluation of formulation was carried out, and results were found to be within the specification range. The antiaging activity was evaluated using an antielastase method. The formulation exhibits good antiaging activity. The sunscreen activity was assessed using the sun protection factor and boot star rating.

Results

The hydrogel formulation showed promising antiaging activity by inhibiting collagenase and elastase enzymes. The formulation showed an SPF of 13.72 and a Boot Star rating of 2, indicating it is an effective sunscreen agent. Also, the formulation was found to be a good moisturizing agent. The present study concluded that crocin and bakuchiol extract formulations effectively combat ageing process and also act as good sunscreen agents.

Conclusion

The topical hydrogel formulation demonstrated promising anti-aging properties and moderate UV protection.

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2025-01-27
2025-09-15

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/content/journals/cosci/10.2174/0126667797337817250113103210
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Hydrogel Formulation Containing Crocin Rich Extract from Nyctanthes Arbor-tristis and Bukuchiol-rich Extract from the Seeds of Psoralea Corylifolia Exhibits Antiaging and Sunscreen Activity
Curr. Cosm. Sci. 4, E26667797337817 (2025); https://doi.org/10.2174/0126667797337817250113103210
/content/journals/cosci/10.2174/0126667797337817250113103210
/content/journals/cosci/10.2174/0126667797337817250113103210
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  • Article Type:     Research Article
Keyword(s): antiaging activity; collagenase; elastase; Nyctanthes arbor-tristis; Psoralea corylifolia; sunscreen activity

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