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- ISSN: 1570-1794
- E-ISSN: 1875-6271
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Direct Propargylic Substitution of Hydroxyl Group in Propargylic Alcohols
- Source: Current Organic Synthesis, Volume 5, Issue 1, Feb 2008, p. 28 - 32
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- 01 Feb 2008
Abstract
Nucleophilic substitution reactions involving propargylic alcohols are important because the alkynyl group can be subsequently transformed into a variety of functional groups. This review summarizes recent direct substitution reactions of hydroxyl groups in propargylic alcohols, reactions that are highly desirable due to atom efficiency and environmental concerns.
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